Acne - Makhopho
https://en.wikipedia.org/wiki/Acne
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References
Diagnosis and treatment of acne 23062156Makhopho, boemo bo atileng haholo ba letlalo United States, ke bothata bo sa khaotseng ba letlalo la ho ruruha. Kalafo e ikemiselitse ho sebetsana le lintlha tse 'nè tse tlatsetsang ho hlahisa li-acne: tlhahiso e feteletseng ea sebum, letlalo la lisele tsa letlalo, Propionibacterium acnes colonization, le ho ruruha ho bakoang ke ho ruruha. Li-retinoids tsa lihlooho li sebetsana ka katleho le liso tsa ho ruruha le tse sa hlabang ka ho thibela le ho fokotsa li-comedone ha li ntse li sebetsana le ho ruruha. Benzoyl peroxide, e fumanehang ka lebenkeleng, ke moemeli oa bactericidal ntle le ho khothaletsa khanyetso ea baktheria. Le hoja lithibela-mafu tsa lihlooho le tsa molomo li sebetsa li le mong, ho li kopanya le li-retinoids tsa lihlooho li ntlafatsa katleho ea tsona. Ho eketsa benzoyl peroxide kalafong ea lithibela-mafu ho theola kotsi ea ho hanyetsa baktheria. Isotretinoin ea molomo, e amohelehang bakeng sa li-acne tse matla le tse manganga, e tsamaisoa ka lenaneo la iPLEDGE.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Guidelines of care for the management of acne vulgaris 26897386Liphekolo tse tloaelehileng tsa li-acne li kenyelletsa benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Lithibela-mafu tsa molomo ke khale e le karolo ea bohlokoa ea kalafo ea makhopho, haholoholo maemong a itekanetseng ho isa ho a matla. Li sebetsa hantle ha li sebelisoa hammoho le topical retinoid le BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin kaofela li bontšitse bopaki ba katleho.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Acne Vulgaris: Diagnosis and Treatment 31613567Li-retinoids tsa lihlooho li lula li khothaletsoa ho phekola makhopho. Ha o sebelisa lithibela-mafu tsa systemic kapa tsa topical, ho bohlokoa ho li kopanya le benzoyl peroxide le retinoids, empa ho fihlela libeke tse 12 feela. Isotretinoin e boloketsoe linyeoe tse matla tsa maqoqomete a sa kang a arabela liphekolo tse ling. Leha ho na le bopaki bo itseng bakeng sa kalafo ea 'mele joalo ka laser therapy le peels ea lik'hemik'hale, hammoho le mekhoa e tlatselletsang joalo ka chefo ea linotsi e hloekisitsoeng le lijo tse itseng, katleho ea tsona e ntse e sa tsejoe.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Effects of Diet on Acne and Its Response to Treatment 32748305 NIH
Liphuputso tse 'maloa li shebile hore na lijo tse fapaneng li ama li-acne joang ho bakuli. Ba fumane hore batho ba nang le li-acne ba jang lijo tse nang le moroalo o tlaase oa glycemic ba atisa ho ba le matheba a fokolang ha ba bapisoa le ba jang lijo tse nang le moroalo o phahameng oa glycemic. Lebese le boetse le ithutoa mabapi le makhopho. Ho bonahala eka liprotheine tse ling tse lebeseng li ka kenya letsoho ho feta mafura kapa lihlahisoa tsa lebese ka kakaretso. Lipatlisiso tse ling li tsepamisitse maikutlo ho omega-3 fatty acids le γ-linoleic acid. E fana ka maikutlo a hore batho ba nang le li-acne ba ka rua molemo ka ho ja litlhapi tse ngata le oli e phetseng hantle ho eketsa tšebeliso ea bona ea mafura ana a mafura. Liphuputso tsa morao-rao tse mabapi le li-probiotics bakeng sa makhopho li bonts'a liphetho tse ts'episang, empa lipatlisiso tse ling lia hlokahala ho netefatsa liphuputso tsena tsa pele.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Ho batho ba bong ka bobeli, lihomone tse bitsoang androgens li bonahala e le karolo ea mokhoa o ka sehloohong, ka ho baka tlhahiso e eketsehileng ea sebum. Ntho e 'ngoe e tloaelehileng ke khōlo e feteletseng ea baktheria Cutibacterium acnes, e teng letlalong.
Liphekolo tse sebelisoang ka ho toba letlalong le amehileng, tse kang azelaic acid, benzoyl peroxide, le salicylic acid, li sebelisoa hangata. Lithibela-mafu le li-retinoids li fumaneha ka mekhoa e sebelisoang letlalong le ho nkoa ka molomo bakeng sa phekolo ea makhopho. Leha ho le joalo, ho hanyetsa lithibela-mafu ho ka hlaha ka lebaka la phekolo ea lithibela-mafu. Mefuta e mengata ea lipilisi tsa thibelo ea bokhachane e ka thusa ho thibela makhopho ho basali. Kalafo ea pele le e mabifi ea li-acne ho sebelisa isotretinoin e ka thusa ho fokotsa bothata ba nako e telele ho batho ka bomong.
○ Kalafo
Gel ea Adapalene e ka sebelisoa haholo hobane e hatella secretion ea sebum mme e na le phello ea ho hatella ho khutla ha makhopho. Gel ea Adapalene e ka halefisa letlalo haeba e sebelisoa haholo qalong. Benzoyl peroxide le azelaic acid, ka lehlakoreng le leng, li ka sebelisoa libakeng tsa ho ruruha ha li-acne hobane li thusa ka ho ruruha. Ka kakaretso, phekolo ea nako e telele ea khoeli ea 1 kapa ho feta e hlokahala ho bona phello.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction