Amyloidosis
☆ Liphethong tsa 2022 Stiftung Warentest tse tsoang Jeremane, khotsofalo ea bareki ka ModelDerm e ne e le tlase hanyane ho feta lipuisano tse lefelloang tsa telemedicine.
Likarolo tsa sefahleho tsa khale tsa Amyloidosis
References
Mosali ea lilemo li 26 o ile a tla tleliniking ea rona a tletleba ka lekhopho le hlohlonang maotong leo a bileng le lona ka lilemo tse 10. Ho sa tsotellehe ho sebelisa litlolo tsa steroid le tranelate ea tazarotene, lekhopho ha lea ka la ntlafala. O ne a se na nalane ea lelapa e amehang. Ha re mo hlahloba, re ile ra fumana mabala a phahamileng, a mahoashe ka pele maotong a hae, a tšoanang le lefu le bitsoang lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
Lichen Amyloidosis ke boemo bo sa tloaelehang ba letlalo bo amanang le ho hlohlona ho sa tsejoeng ka lebaka le sa tsejoeng. E bonahala e le lihlopha tsa maqeba a phahamisitsoeng, a sootho karolong e ka ntle ea letlalo. Lichen Amyloidosis hangata e hlaha ho batho ba lilemo tse 50 ho isa ho 60 mme ka bomalimabe, ha ho pheko bakeng sa eona. Liphekolo tse teng hona joale hangata ha li sebetse hantle.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen amyloidosis ke ho hlohlona ha letlalo ka nako e telele. E tsebahala ka lihlopha tsa makukuno a teteaneng a fumanehang ka mokokotlong, liropeng, liropeng le matsohong. Ha e hlahlojoa ka tlas'a microscope, Lichen amyloidosis e bontša ho bokellana ha amyloid karolong e ka holimo ea letlalo hammoho le ho tiea le ho atolosoa ha lesela le ka ntle la letlalo. Leha ho sa utloisisoe hantle hore na sesosa sa Lichen amyloidosis ke sefe, liphuputso tse fetileng li e amahanya le lintho tse kang ho hohla kapa ho hohlana ha letlalo, lefu la lisele, tšoaetso ea vaerase, har'a tse ling. Lichen amyloidosis e bonahala e hokahane le maemo a mang a mangata a letlalo (atopic dermatitis, lichen planus, mycosis fungoides) .
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
○ Tlhahlobo le Kalafo
#Electrophoresis of blood or urine
#Skin biopsy