Melasma
https://en.wikipedia.org/wiki/Melasma
☆ Liphethong tsa 2022 Stiftung Warentest tse tsoang Jeremane, khotsofalo ea bareki ka ModelDerm e ne e le tlase hanyane ho feta lipuisano tse lefelloang tsa telemedicine. 

Ke boemo bo tloaelehileng bo bonoang ho basali ba Asia ba lilemong tsa bona tsa bo-40. Leqeba le pota-potiloeng setšoantšong le haufi le lentigo ho e-na le melasma.
relevance score : -100.0%
References
Efficacy and Safety of Tranexamic Acid in Melasma: A Meta-analysis and Systematic Review 28374042Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
The Low-Fluence Q-Switched Nd:YAG Laser Treatment for Melasma: A Systematic Review 35888655 NIH
Haufinyane tjena, low-fluence Q-switched Nd:YAG (LFQSNY) laser e se e tumme ka ho alafa melasma, haholo Asia. Ho akaretsa lithuto tse fapaneng ho ne ho le thata, empa LFQSNY e bonahala e sebetsa hantle ebile e bolokehile bakeng sa melasma ha e bapisoa le liphekolo tsa setso. Leha ho le joalo, linyeoe tse ling tsa mottled hypopigmentation li tlalehiloe e le litlamorao tsa LFQSNY, mohlomong ka lebaka la matla a phahameng a laser. Tšebeliso e matla ea LFQSNY le eona e ka lebisa ho hyperpigmentation ho tsoa ho ruruha, haholo-holo letlalong le lefifi.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Pigmentation Disorders: Diagnosis and Management 29431372Hangata mathata a pigmentation a fumanoa tlhokomelong ea mantlha. Mefuta e tloaelehileng ea mafu a hyperpigmentation e kenyelletsa post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Melasma e ke ke ea rarolloa ka kalafo ea laser ka nako e itseng, kaha ke lefu leo ho lona pigment e tsoelang pele e hlahisoang. Tranxenemic acid e thusa ho ntlafatsa ho fokotsa mebala.
○ Kalafo
Linaheng tse ling (mohlala, Japane, Korea), oral tranexamic acid e fumaneha ka holim'a counter 'me e sebetsa hantle. Setlolo sa melasma se nang le tranexamic acid le azelaic acid se ka thusa hanyane.
Hydroquinone e ka sebelisoa ka holimo bakeng sa kalafo ea hyperpigmentation, empa FDA e ile ea emisa lihlahisoa tsa OTC tse nang le hydroquinone ho tloha ka 2020.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma