Onychomysosis
☆ Liphethong tsa 2022 Stiftung Warentest tse tsoang Jeremane, khotsofalo ea bareki ka ModelDerm e ne e le tlase hanyane ho feta lipuisano tse lefelloang tsa telemedicine.
Lenala le anngoeng ke Onychomysosis
Leoto la motho le nang le tšoaetso ea fungal manala libeke tse leshome nakong ea ho noa meriana ea terbinafine. Ela hloko sehlopha sa kholo e phetseng hantle ea manala ka mor'a lipekere tse setseng tse nang le tšoaetso.
References
Li-antifungal tsa systemic ke tsona kalafo e sebetsang ka ho fetisisa. Meta-analysis e bontša litekanyetso tsa phekolo ea mycotic ka tsela e latelang: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48% . Ho senyeha ha manala ka nako e le 'ngoe ho eketsa litekanyetso tsa phekolo. Kalafo ea sehlooho e nang le ciclopirox ha e sebetse hantle; e na le sekhahla sa ho hloleha se fetang 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Onychomycosis ke tšoaetso ea fungal e amang lipekere. Ha e bakoa ke dermatophytes, e bitsoa tinea unguium. Onychomycosis e kenyelletsa tšoaetso e bakoang ke dermatophytes, tomoso le hlobo. Bothata ba manala bo sa bakoang ke tšoaetso ea fungal bo bitsoa nail dystrophy. Le hoja e ka ama menoana le menoana ka bobeli, toenail onychomycosis e tloaelehile haholo. Sengoliloeng sena se bua ka likarolo tse fapaneng tsa toenail onychomycosis, joalo ka phello ea eona, mefuta ea bongaka, mekhahlelo, tlhahlobo le kalafo. Le hoja e se kotsing ea bophelo, onychomycosis e ka lebisa mathateng a tebileng a kang cellulitis, sepsis, tšoaetso ea masapo, tšenyo ea lisele le tahlehelo ea lipekere.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Terbinafine ke moriana o loantšang mafu a fungal ka ho thibela squalene epoxidase. E sebetsa khahlano le mefuta e mengata ea li-fungus tsa letlalo 'me e lumelletsoe ho alafa fungus ea manala ha e nkuoa ka molomo. Le hoja litla-morao tse ngata tse kang hlooho le mathata a mala li nyenyane 'me li itsamaela ka botsona, liphetoho tsa tatso (dysgeusia) li ka fapana ho tloha ho tse bonolo ho ea ho tse matla, ka linako tse ling li lebisa ho theola boima ba' mele. Liphetoho tse sa feleng tsa tatso ha lia tloaeleha empa li tlalehiloe.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Onychomycosis ke tšoaetso ea fungal e amang lipekere. Hoo e ka bang 90% ea mafu a menoana le 75% ea mafu a menoana a bakoa ke li-fungus (Trichophyton mentagrophytes, Trichophyton rubrum) . Matšoao a kenyeletsa ho fifala ha manala, ho teteana, ho arohana le bethe ea manala le ho hola ho feta tekano. Kalafo hangata e kenyelletsa litlhare tse nooang joalo ka terbinafine kapa itraconazole, 'me kalafo ea mantlha ke khetho bakeng sa linyeoe tse bobebe ho isa ho tse itekanetseng.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
Moriana oa antifungal terbinafine o nkiloeng ka molomo o bonahala o sebetsa ka ho fetisisa empa terbinafine e amahanngoa le phello e ka thōko ea sebete.
Onychomysosis e etsahala ho hoo e ka bang liphesente tse 10 tsa batho ba baholo, 'me batho ba baholo ba ameha khafetsa. Tse tona li angoa hangata ho feta tse tšehali. Onychomysosis e emela hoo e ka bang halofo ea lefu la manala. Sena se bolela hore ho holofala ha manala a menoana ho ka boela ha hlaha ho tsoa lisosa tse ling ntle le onychomycosis.
○ Kalafo - Lithethefatsi tsa OTC
Ho thata ho phekola onychomycosis ka meriana ea lihlooho hobane ho thata hore lithethefatsi li kenelle menoaneng e teteaneng.
#Ketoconazole
#Clotrimazole
#Miconazole
#Terbinafine
#Butenafine [Lotrimin]
#Tolnaftate
○ Kalafo
Kalafo ea nako e telele hangata e hlokahala ho fihlela lenala le nang le tšoaetso le tlosoa ka ho feletseng.
#Terbinafine (oral)
#Itraconazole
#Efinaconazole lacquer [Jublia]
#Ciclopirox lacquer