Panniculitis - Lefu La Panniculitishttps://en.wikipedia.org/wiki/Panniculitis
Lefu La Panniculitis (Panniculitis) ke sehlopha sa mafu ao letšoao la ona e leng ho ruruha ha lisele tse tlase tsa adipose. Matšoao a kenyeletsa maqhutsu a bonolo a letlalo, le matšoao a tsamaiso a kang ho theola boima ba 'mele le mokhathala.

"Erythema nodosum" ke mofuta oa lefu la panniculitis (panniculitis) o khetholloang ke maqhutsu a mafubelu a bonolo, 1-10 cm, a amahanngoa le matšoao a tsamaiso a kenyeletsang feberu, malaise le bohloko ba manonyeletso. Maqhutsu a ka kokobela nakong ea libeke tse 2-6 ntle le ho tsoa liso kapa maqeba. Erythema nodosum e amahanngoa le ts'oaetso, ho kenyelletsa Hepatitis C, EBV le lefuba, bokhachane, Non-Hodgkin lymphoma, le kankere ea pancreatic.

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References Erythema Nodosum: A Practical Approach and Diagnostic Algorithm 33683567 
NIH
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
 Panniculitis in Children 34449587 
NIH
Panniculitis theha sehlopha sa mefuta e fapaneng ea mafu a ho ruruha a kenyelletsang lithane tse tlase tsa adipose. Mathata ana a hlaha ka seoelo baneng. The panniculitis e ka ba mokhoa o ka sehloohong oa ts'oaetso ea tsamaiso kapa ts'ebetso ea bobeli e bakoang ke tšoaetso, ho sithabela kapa ho pepesehela meriana. Mefuta e mengata ea panniculitis e na le pontšo e tšoanang ea kliniki (ho sa tsotellehe hore na etiology ke efe) , e nang le maqhutsu a bonolo, a erythematous subcutaneous.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
 Erythema nodosum - a review of an uncommon panniculitis 24746312
Panniculitis , ho ruruha ha mafura a subcutaneous, hangata ho hlahisa li-nodule tsa ho ruruha. Erythema nodosum (EN) ke mokhoa oa bongaka o atisang ho hlaha oa panniculitis. Le hoja ho fihla ho 55% ea EN e nkoa e le idiopathic, lisosa tse tloaelehileng ka ho fetisisa li kenyelletsa tšoaetso, lithethefatsi, mafu a tsamaiso a kang sarcoidosis le lefu la ho ruruha ha mala, boimana le bofokoli. EN hangata e hlahisa lilemong tsa bocha le tsa bo-20, 'me e bonoa hangata ho basali. Hangata e etelloa pele ke prodrome e sa khetheheng ea beke e le 'ngoe ho isa ho tse tharo, e ka kenyelletsang feberu, malaise, le matšoao a tšoaetso e holimo ea matšoafo. Ka mor'a moo, ho latela maqeba a maqeba, 'me hangata a fumanoa sebakeng sa extensor ea maoto le matsoho. Maqeba a bohloko a chitja kapa a oval, a phahamisitsoe hanyenyane, maqhutsu a khubelu a se nang seso. Pathogenesis e nepahetseng ea EN ha e utloisisoe, leha ho nahanoa hore e bakoa ke ho beoa ha li-immune complexes ka har'a li-septae ka mafura a subcutaneous, a bakang neutrophilic panniculitis. Le ntle le kalafo e khethehileng bakeng sa boemo bo bakang, EN e rarolla ntle le kalafo maemong a mangata.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.