Inpo leuwih ― Urang sundan

Hiji awéwé umur 26 taun datang ka klinik kami kalayan keluhan baruntus gatal dina suku na, anu geus karandapan salila 10 taun. Sanajan geus ngagunakeun krim stéroid jeung krim tazarotene, baruntusna teu membaik. Anjeunna teu boga riwayat kulawarga anu relevan. Nalika dipariksa, kapanggih aya lesi kasar di hareup suku na, nu cocog jeung diagnosis lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.

Lichen Amyloidosis mangrupikeun kaayaan kulit anu jarang, dipatalkeun jeung gatel anu terus-terusan alatan sabab anu teu dipikanyaho. Biasana muncul salaku gugusan bintik-bintik anu ngagedé, warna na robah dina permukaan kulit. Lichen Amyloidosis biasana muncul dina jalma umur 50 nepi ka 60 taun, sarta hanjakalna teu aya ubar pikeun éta. Pangobatan anu sayogi ayeuna biasana teu tiasa ngahasilkeun hasil anu saé.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.

Lichen amyloidosis mangrupikeun kaayaan kulit anu gatal sareng berkepanjangan. Ieu dipikawanoh ku klaster nabrak anu kandel, utamana kapanggih di tonggong, tulang tonggong, pingping, jeung leungeun. Nalika ditilik dina mikroskop, Lichen amyloidosis nunjukkeun akumulasi amiloid dina lapisan luhur kulit sarta penebalan jeung pembesaran epidermis. Sanaos panyabab pasti Lichen amyloidosis teu acan kahartos sacara lengkep, panalungtikan saméméhna geus ngaitkeun kana faktor-faktor sapertos gesekan kulit, apoptosis sél, inféksi virus, jeung sajabana. Lichen amyloidosis sigana dikaitkeun sareng sababaraha kaayaan kulit sanés (atopic dermatitis, lichen planus, mycosis fungoides).
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.