Erythema multiforme - Érythema Multiforme
☆ Dina hasil Stiftung Warentest 2022 ti Jerman, kapuasan konsumen sareng ModelDerm ngan ukur langkung handap tibatan konsultasi telemedicine anu mayar.
Erythema multiforme minor ― Catet yén puseur lesions bisa blanch.
Urtikaria ogé bisa dianggap salaku diagnosis diferensial.
References
Erythema multiforme (EM) mangrupikeun kaayaan dimana bintik-bintik anu siga target muncul dina kulit sareng mémbran mukosa kusabab réaksi imun. Sanajan mindeng dipicu ku inféksi viral, utamana virus herpes simpléks (HSV) , atawa pangobatan tangtu, cukang lantaranana tetep kanyahoan dina loba kasus. Ngubaran EM akut museurkeun kana ngaleungitkeun gejala nganggo krim anu ngandung stéroid atanapi antihistamin. Ngatur EM ngulang téh paling éféktif lamun tailored ka unggal sabar. Pendekatan awal ngalibatkeun perlakuan lisan sareng topikal. Ieu kalebet kortikosteroid sareng pangobatan antiviral. Pangobatan topikal diwangun ku krim stéroid anu kuat sareng solusi pikeun mémbran mukosa anu kapangaruhan. Pikeun pasien anu henteu ngaréspon kana antiviral, pilihan jalur kadua kalebet ubar anu ngahambat kekebalan, antibiotik, anthelmintik, sareng antimalarial.
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Dina sababaraha kasus, erythema multiforme hampang leungit sorangan dina 2 nepi ka 4 minggu. Sindrom Stevens-Johnson, kaayaan parna anu mangaruhan mémbran mukosa, tiasa dugi ka 6 minggu. Stéroid biasana henteu disarankeun pikeun kasus anu hampang. Naha stéroid kudu dipaké pikeun erythema multiforme parna teu pasti sabab euweuh papanggihan jelas tina studi randomized nunjukkeun barudak nu bakal nguntungkeun tina perlakuan ieu.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
Kami nampilkeun kasus lisan erythema multiforme (EM) disababkeun ku TMP/SMX , némbongkeun borok lisan jeung biwir has tanpa lesions kulit. Ieu negeskeun kabutuhan pikeun ngabédakeunana tina gangguan ulcerative lisan anu sanés. Sabar narima perlakuan symptomatic sarta tablet prednisolone, anjog ka perbaikan sanggeus stopping terapi TMP / SMX.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
Erythema multiforme mangrupakeun réaksi ngalibetkeun kulit sarta kadangkala mukosa, dipicu ku sistim imun. Ilaharna, éta manifests salaku lesions target-kawas, nu bisa muncul terasing, recur, atawa persist. Lesi ieu biasana mangaruhan sacara simetris kana ekstremitas, khususna permukaan luarna. Panyabab utama kalebet inféksi sapertos virus herpes simpléks sareng Mycoplasma pneumoniae, ogé pangobatan, imunisasi, sareng panyakit otoimun. Ngabédakeun erythema multiforme ti urticaria gumantung kana lilana lesions; erythema multiforme lesi tetep tetep sahenteuna sahenteuna tujuh dinten, sedengkeun lesi urtikaria sering ngaleungit dina sadinten. Sanaos sami, penting pisan pikeun ngabédakeun erythema multiforme tina sindrom Stevens-Johnson anu langkung parah, anu biasana nunjukkeun macules erythematous atanapi purpuric sareng lepuh. Ngatur erythema multiforme ngalibatkeun relief gejala sareng stéroid topikal atanapi antihistamin sareng ngungkulan panyababna. Pikeun kasus kambuh pakait sareng virus herpes simpléks, terapi antiviral prophylactic disarankeun. Keterlibatan mukosa parah tiasa ngabutuhkeun rumah sakit pikeun cairan intravena sareng ngagantian éléktrolit.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Kaayaanna beda-beda ti anu hampang, baruntus mandiri dugi ka parah, bentuk anu ngancam kahirupan anu katelah erythema multiforme major anu ogé ngalibatkeun mémbran mukosa. Invasi mémbran mukosa atanapi ayana bula mangrupikeun tanda-tanda parah parah.
- Erythema multiforme minor: target has atanapi diangkat, papules edematous disebarkeun acrally
Bentuk anu hampang biasana muncul sareng rada gatel (tapi gatel tiasa parah pisan), bintik-bintik pink-beureum, disusun sacara simetris sareng dimimitian dina tungtung. Resolusi baruntus dina 7-10 dinten mangrupikeun norma dina bentuk panyakit ieu.
- Erythema multiforme major: target has atawa diangkat, papules edematous disebarkeun acrally kalawan involvement hiji atawa leuwih mémbran mukosa. Detasemen épidermis ngalibatkeun kirang ti 10% tina total luas permukaan awak.
○ Perlakuan - Narkoba OTC
Upami dibarengan ku muriang (suhu awak naék), disarankeun pikeun nganjang ka rumah sakit sagancangna.
Obat-obatan anu disangka kedah dileungitkeun. (misalna antibiotik, ubar anti radang nonsteroidal)
Antihistamines lisan kayaning cetirizine na loratadine pikeun itching.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]