Onychomysosis
☆ Dina hasil Stiftung Warentest 2022 ti Jerman, kapuasan konsumen sareng ModelDerm ngan ukur langkung handap tibatan konsultasi telemedicine anu mayar.
Kuku suku kapangaruhan ku Onychomysosis
Suku hiji jalma kalawan inféksi kuku jamur sapuluh minggu kana kursus nginum obat lisan terbinafine. Catet pita tumuwuhna kuku séhat tukangeun kuku kainféksi sésana.
References
Antifungal sistemik mangrupikeun pangobatan anu paling mujarab. Meta-analysis nembongkeun tingkat penyembuhan mycotic saperti kieu: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48% . Debridement kuku concomitant salajengna ngaronjatkeun ongkos cageur. Terapi topikal sareng ciclopirox kirang efektif; eta boga laju gagalna ngaleuwihan 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Onychomycosis mangrupikeun inféksi jamur anu mangaruhan kuku. Nalika éta disababkeun ku dermatophytes, éta disebut tinea unguium. Onychomycosis ngawengku inféksi disababkeun ku dermatophytes, yeasts, sarta kapang. Masalah kuku teu disababkeun ku inféksi jamur disebut nail dystrophy. Sanajan eta bisa mangaruhan duanana fingernails na toenails, toenail onychomycosis leuwih umum. Artikel ieu ngabahas sagala rupa aspék onychomycosis kuku suku, kayaning dampak na, jenis klinis, tahapan, diagnosis, jeung perlakuan. Sanaos henteu ngancam kahirupan, onychomycosis tiasa nyababkeun komplikasi serius sapertos selulitis, sepsis, inféksi tulang, karusakan jaringan, sareng leungitna kuku.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Terbinafine mangrupakeun ubar nu ngalawan inféksi jamur ku blocking squalene epoxidase. Éta mujarab ngalawan seueur jinis jamur kulit sareng disatujuan pikeun ngubaran jamur kuku nalika dicandak sacara lisan. Bari paling efek samping kawas headaches jeung masalah burih anu minor sarta dileungitkeun sorangan, parobahan rasa (dysgeusia) bisa rupa-rupa ti hampang mun parna, sakapeung ngabalukarkeun leungitna beurat. Parobahan rasa permanén jarang tapi geus dilaporkeun.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Onychomycosis mangrupikeun inféksi jamur anu mangaruhan kuku. Sakitar 90% inféksi kuku suku sareng 75% inféksi kuku ramo disababkeun ku jamur (Trichophyton mentagrophytes, Trichophyton rubrum) . Gejala kaasup discoloration kuku, thickening, separation tina ranjang kuku, sarta overgrowth. Perlakuan biasana ngalibatkeun pangobatan lisan sapertos terbinafine atanapi itraconazole, kalayan pangobatan topikal janten pilihan pikeun kasus anu hampang dugi ka sedeng.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
Pangobatan antifungal terbinafine anu dicandak ku sungut sigana anu paling efektif tapi terbinafine aya hubunganana sareng efek samping ati.
Onychomysosis lumangsung dina kira-kira 10 persén populasi sawawa, kalawan lansia leuwih remen kapangaruhan. Jalu kapangaruhan langkung sering tibatan awéwé. Onychomysosis ngagambarkeun kira satengah tina kasakit kuku. Ieu ngandung harti yén deformity tina toenails ogé bisa datangna ti sabab lian ti onychomycosis.
○ Perlakuan - Narkoba OTC
Hésé pikeun ngubaran onikomikosis ku pangobatan topikal sabab hésé pikeun ubar pikeun nembus kuku suku anu kandel.
#Ketoconazole
#Clotrimazole
#Miconazole
#Terbinafine
#Butenafine [Lotrimin]
#Tolnaftate
○ Perlakuan
Perlakuan jangka panjang biasana diperlukeun nepi ka kuku suku nu kainféksi sagemblengna dipiceun kaluar.
#Terbinafine (oral)
#Itraconazole
#Efinaconazole lacquer [Jublia]
#Ciclopirox lacquer