Prurigo nodularis
☆ Dina hasil Stiftung Warentest 2022 ti Jerman, kapuasan konsumen sareng ModelDerm ngan ukur langkung handap tibatan konsultasi telemedicine anu mayar.
References
Prurigo nodularis mangrupakeun kaayaan kulit tahan lila dicirikeun ku sababaraha nabrak sungut jeung nodules, biasana kapanggih dina bagian luar leungeun jeung suku. Benjolan ieu tiasa rupa-rupa warna tina warna daging dugi ka pink sareng gatal pisan. Éta tiasa mangaruhan jalma umur naon waé sareng sering dikaitkeun sareng kaayaan kulit sanés anu nyababkeun gatal kronis, sapertos dermatitis atopik. Pilihan pangobatan kalebet pangobatan anti ateul anu kuat, ubar anu mangaruhan sistem imun, sareng pangobatan anu nargétkeun sistem saraf. Ngatur prurigo nodularis biasana ngalibatkeun terapi jangka panjang.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Perawatan biasana ngalibatkeun ngagunakeun krim atanapi suntikan stéroid dina daérah anu kapangaruhan. Dina kasus anu langkung parna atanapi nekad, pangobatan sapertos terapi cahaya atanapi pangobatan anu ngirangan sistem imun tiasa diperyogikeun. Thalidomide sareng lenalidomide mangrupikeun pilihan pikeun kasus parna, tapi tiasa gaduh efek samping anu serius. Pangobatan anu langkung énggal (opioid receptor antagonists, neurokinin-1 receptor antagonists) nunjukkeun janji pikeun ngubaran prurigo nodularis kalayan efek samping anu langkung sakedik dibandingkeun thalidomide atanapi lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Chronic prurigo mangrupikeun kaayaan kulit anu dicirikeun ku gatal-gatal anu berkepanjangan (langgeng langkung ti 6 minggu) , lesi kulit anu aya hubunganana sareng goresan, sareng riwayat sering goresan. Ieu ngawengku neuroinflammation na fibrosis dina kulit.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Prurigo nodularis mangrupikeun masalah kulit anu berkepanjangan anu ditandaan ku nodul gatal. Kami henteu terang naon anu nyababkeun éta, tapi sigana masalah imun sareng saraf maénkeun peran dina siklus gatal-gatal. Ayeuna, teu aya pangobatan anu disatujuan ku FDA AS khusus pikeun prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
○ Perlakuan - Narkoba OTC
Ngumbah wewengkon lesion ku sabun teu mantuan jeung bisa nyieun leuwih parah. Salep stéroid OTC tiasa ngabantosan gejala, tapi biasana kedah diterapkeun sababaraha minggu pikeun ningkatkeun. Nuluykeun nyandak antihistamines ogé mantuan ngagentos itching nu.
#OTC steroid ointment
#OTC antihistamine
○ Perlakuan
#Intralesional triamcinolone injection