Syphilis - Sipilis
https://su.wikipedia.org/wiki/Sifilis
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Sifilis sekunder
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References
Secondary syphilis in cali, Colombia: new concepts in disease pathogenesis 20502522 NIH
Sipilis nyaéta kasakit anu ditularkeun sacara séksual disababkeun ku baktéri Treponema pallidum. Dina ulikan ieu, urang difokuskeun kana 57 penderita umur 18‑68 taun anu ngalaman sipilis sekundér.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Syphilis 30521201 NIH
Sipilis mangrupikeun inféksi baktéri anu disababkeun ku Treponema pallidum. Bisa niru rupa‑rupa panyakit, dipikawanoh minangka “great imitator”. Sipilis masih mangaruhan jutaan jalma di sakuliah dunya, tapi tiasa diubaran sacara efektif ku penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis 29022569 NIH
Treponema pallidum ngabalukarkeun sifilis ngaliwatan kontak seksual atawa ti indung ka orok nalika kakandungan. Sanaos aya tés saderhana pikeun ngadiagnosa éta jeung pangobatan kalayan hiji suntikan penicillin jangka panjang tiasa dipaké, sifilis janten masalah ageung deui di dunya. Ieu hususna leres di antara lalaki anu ngalakukeun hubungan seksual sareng lalaki (MSM) di nagara kalayan panghasilan luhur jeung sedeng. Sanaos sababaraha nagara panghasilan rendah parantos nyumponan tujuan WHO pikeun ngeureunkeun sifilis ti indung ka orok, aya paningkatan anu pikahariwangeun dina sifilis di antara MSM anu HIV‑positif.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Congenital Syphilis 30725772 NIH
(1) Enlarged Ati: Ieu mindeng kapanggih sarta bisa lumangsung barengan jeung limpa anu enlarged. Mariksa biopsi ati ku mikroskop darkfield tiasa nembongkeun ayana spirochete. Tes fungsi ati tiasa nunjukkeun abnormalitas. (2) Kulit konéng (jaundice): Nunjukkeun jaundice gumantung kana sabaraha ati anu kapangaruhan. (3) Irung runny: Mindeng jadi salah sahiji tanda munggaran, biasana muncul dina minggu kahiji sanggeus lahir. (4) Titik limfa ngabareuhan: Bareuh umum tina titik limfa, biasana teu nyeri, sarta sering kapanggih. (5) Rashes Kulit: Baruntus ilaharna mucunghul hiji nepi ka dua minggu sanggeus irung runny. Anjeun tiasa ningali bintik beureum atawa pink leutik dina tonggong, imbit, pingping, jeung dampal suku. Baruntus ieu bisa maju jadi peeling jeung crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Diagnosis sareng Perawatan
VDRL sareng RPR tiasa dianggo pikeun ngonfirmasi inféksi sareng pikeun skrining sipilis. Tés FTA‑ABS mangrupikeun tés anu langkung spésifik sareng tiasa dianggo pikeun mariksa sajarah inféksi saméméhna. Penicillin dipaké pikeun ngubaran sipilis.