Syphilis - Sipilis
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Chancres ― inféksi sipilis primér ku Treponema pallidum
References
Sipilis nyaéta kasakit dikirimkeun séksual disababkeun ku baktéri Treponema pallidum. Dina ulikan ieu, urang difokuskeun 57 penderita yuswa 18-68 jeung sipilis sekundér.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Sipilis mangrupikeun inféksi baktéri anu disababkeun ku Treponema pallidum. Bisa meniru rupa-rupa panyakit, meunang nickname great imitator. Sipilis masih mangaruhan jutaan jalma sacara global tapi tiasa diubaran sacara efektif ku pénisilin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum ngabalukarkeun sipilis ngaliwatan kontak seksual atawa ti indung ka orok nalika kakandungan. Sanaos aya tés saderhana pikeun ngadiagnosis éta sareng pengobatan kalayan hiji suntikan pénisilin jangka panjang tiasa dianggo, sifilis janten masalah ageung deui di dunya. Ieu hususna leres diantara lalaki anu gaduh sex sareng lalaki (MSM) di nagara anu panghasilan luhur sareng sedeng. Sanaos sababaraha nagara berpendapatan rendah parantos nyumponan tujuan WHO pikeun ngeureunkeun sifilis ti indung ka orok, aya paningkatan anu pikahariwangeun dina sifilis diantara MSM anu positif HIV.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Enlarged Ati: Ieu mindeng kapanggih sarta bisa lumangsung barengan hiji limpa enlarged. Mariksa biopsi ati dina mikroskop darkfield tiasa nembongkeun ayana spirochete. Tes fungsi ati tiasa nunjukkeun abnormalitas. (2) Kulit konéng (jaundice) : Naha aya jalma nunjukkeun jaundice gumantung kana sabaraha ati anu kapangaruhan. (3) Irung runny: Mindeng salah sahiji tanda munggaran, biasana dina minggu kahiji sanggeus lahir. (4) Titik limfa ngabareuhan: Bareuh umum tina titik limfa, biasana henteu aya rasa nyeri, ogé umum. (5) Rashes Kulit: A baruntus ilaharna mucunghul hiji nepi ka dua minggu sanggeus irung runny. Anjeun tiasa ningali bintik beureum atanapi pink leutik dina tonggong, imbit, pingping, sareng dampal suku. Baruntus ieu bisa maju ka peeling na crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Diagnosis sareng Perawatan
VDRL sareng RPR tiasa dianggo pikeun ngonfirmasi inféksi sareng layar pikeun sipilis. Tés FTA-ABS mangrupikeun tés anu langkung spésifik sareng tiasa dianggo pikeun mariksa sajarah inféksi saméméhna. Pénisilin dipaké pikeun ngubaran sipilis.