Dermatofibroma - Dermatofibrom
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Typiskt fall av Dermatofibrom (Dermatofibroma) ― En hård knöl på extremiteten. Dermatofibrom (Dermatofibroma) är en relativt vanlig godartad tumör.
References
Dermatofibroma är en vanlig hudsjukdom som oftast finns på armar eller ben. Det ser ut som fasta klumpar under huden, ofta mindre än 1 centimeter stora. Även om det vanligtvis är smärtfritt, kan det vara kopplat till tidigare mindre skador som insektsbett eller taggstick. Dermatofibrom kan drabba vem som helst men är vanligare hos kvinnor i åldern 20 till 40. De är vanligtvis godartade, men ibland kan de komma tillbaka efter borttagning. Det är viktigt att skilja dermatofibrom från en mer aggressiv hudtumör som kallas dermatofibrosarcoma protuberans.
Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma. These mesenchymal cell lesions of the dermis clinically are firm subcutaneous nodules that occur on the extremities in the vast majority of cases and may or may not be associated with overlying skin changes. They are most commonly asymptomatic and usually relatively small, less than or equal to 1 centimeter in diameter. Often, patients who present with a dermatofibroma relate a history of possibly inciting local trauma at the site, such as from an insect bite or superficial puncture wound from thorns or wood splinters. Dermatofibromas occur in people of all ages, although more commonly during the ages of the 20s to 40s, and develop more frequently in females than males, with as high as a 2:1 female to male predominance according to some reports. They are a benign tumor, although there have been cases of local recurrence, and even more rarely, distant metastases have been reported. When considering the differential diagnosis of these lesions, it is vitally important to distinguish dermatofibromas from dermatofibrosarcoma protuberans, a similar-appearing but more aggressive cutaneous neoplasm.
Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma. These mesenchymal cell lesions of the dermis clinically are firm subcutaneous nodules that occur on the extremities in the vast majority of cases and may or may not be associated with overlying skin changes. They are most commonly asymptomatic and usually relatively small, less than or equal to 1 centimeter in diameter. Often, patients who present with a dermatofibroma relate a history of possibly inciting local trauma at the site, such as from an insect bite or superficial puncture wound from thorns or wood splinters. Dermatofibromas occur in people of all ages, although more commonly during the ages of the 20s to 40s, and develop more frequently in females than males, with as high as a 2:1 female to male predominance according to some reports. They are a benign tumor, although there have been cases of local recurrence, and even more rarely, distant metastases have been reported. When considering the differential diagnosis of these lesions, it is vitally important to distinguish dermatofibromas from dermatofibrosarcoma protuberans, a similar-appearing but more aggressive cutaneous neoplasm.
Den föredragna behandlingen för lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, and epidermoid cysts är kirurgiskt avlägsnande. Cherry angiomas and sebaceous hyperplasia behandlas vanligtvis med laserterapi eller elektrodesikation. Kryoterapi och rakexcision är populära alternativ för acrochordons and seborrheic keratoses. Om en familjeläkare känner sig osäker på att diagnostisera eller behandla en lesion, eller om en biopsi bekräftar melanom, rekommenderas remiss till en specialist.
The preferred treatment for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, epidermoid cysts is surgical removal. Cherry angiomas, sebaceous hyperplasia are commonly treated with laser therapy or electrodesiccation. Cryotherapy and shave excision are popular choices for acrochordons, seborrheic keratoses. If a family physician feels uncertain about diagnosing or treating a lesion, or if a biopsy confirms melanoma, referral to a specialist is recommended.
The preferred treatment for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, epidermoid cysts is surgical removal. Cherry angiomas, sebaceous hyperplasia are commonly treated with laser therapy or electrodesiccation. Cryotherapy and shave excision are popular choices for acrochordons, seborrheic keratoses. If a family physician feels uncertain about diagnosing or treating a lesion, or if a biopsy confirms melanoma, referral to a specialist is recommended.
Dermatofibrom kan bildas som en reaktion på tidigare skador som insektsbett eller taggstick. Dermatofibrom klassas som godartade hudskador, vilket innebär att de är helt ofarliga, även om dermatofibrom kan förväxlas med en mängd olika subkutana tumörer. Djupt penetrerande dermatofibrom kan vara svårt att skilja, även histologiskt, från sällsynta maligna fibrohistocytiska tumörer som "dermatofibrosarcoma protuberans".
○ Diagnos och behandling
De flesta är godartade, men stora lesioner (>5 mm) kan kräva biopsi.
#Dermoscopy
#Skin biopsy