Melasma
☆ I Stiftung Warentest-resultaten 2022 från Tyskland var konsumentnöjdheten med ModelDerm bara något lägre än med betalda telemedicinkonsultationer.
Det är ett vanligt tillstånd som observeras hos asiatiska kvinnor i början av 40-årsåldern. Den inringade lesionen på bilden är närmare lentigo snarare än melasma.
References
Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
Nyligen har low-fluence Q-switched Nd:YAG (LFQSNY) laser blivit populär för behandling av melasma, särskilt i Asien. Att sammanfatta olika studier var utmanande, men LFQSNY verkar generellt sett effektivt och säkert för melasma jämfört med traditionella terapier. Vissa fall av fläckig hypopigmentering har dock rapporterats som en bieffekt av LFQSNY, möjligen på grund av hög laserenergi. Aggressiv användning av LFQSNY kan också leda till hyperpigmentering från inflammation, särskilt i mörkare hudtoner.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Pigmentationsproblem finns ofta inom primärvården. Vanliga typer av hyperpigmenteringsstörningar inkluderar post-inflammatory hyperpigmentation, melasma, sunspots, freckles, and café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Melasma kan inte lösas med laserbehandling under en viss tid, eftersom det är en sjukdom där pigment kontinuerligt produceras. Tranxenemsyra hjälper till att förbättra för att minska pigmenteringen.
○ Behandling
I vissa länder (t.ex. Japan, Korea) finns oral tranexamsyra tillgängligt receptfritt och är effektivt. Melasmakrämen med tranexamsyra och azelainsyra kan vara delvis till hjälp.
Hydrokinon kan användas topiskt för behandling av hyperpigmentering, men FDA stoppade OTC-produkterna som innehåller hydrokinon från och med 2020.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma