Panniculitis - Pannikulit
☆ I Stiftung Warentest-resultaten 2022 från Tyskland var konsumentnöjdheten med ModelDerm bara något lägre än med betalda telemedicinkonsultationer.
Tuberkulos är en av de betydande orsakerna.
References
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis bildar en heterogen grupp av inflammatoriska sjukdomar som involverar den subkutana fettvävnaden. Dessa störningar är sällsynta hos barn. Pannikuliten kan vara den primära processen i en systemisk störning eller en sekundär process som är resultatet av infektion, trauma eller exponering för medicin. De flesta typer av pannikulit har samma kliniska presentation (oavsett etiologi) , med ömma, erytematösa subkutana knölar.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , inflammation i det subkutana fettet, uppträder vanligtvis med inflammatoriska knölar. Erythema nodosum (EN) är kliniskt den vanligaste formen av pannikulit. Medan upp till 55 % av EN anses vara idiopatisk, är de vanligaste orsakerna infektioner, droger, systemiska sjukdomar som sarkoidos och inflammatorisk tarmsjukdom, graviditet och malignitet. EN uppträder vanligtvis i tonåren och 20-talet och ses vanligare hos kvinnor. Det föregås ofta av en ospecifik prodrom på en till tre veckor, som kan innefatta feber, sjukdomskänsla och symtom på en övre luftvägsinfektion. Kutana lesioner följer sedan, vanligtvis lokaliserade på extensoraspekten av extremiteterna. Lesionerna är smärtsamma rundade eller ovala, lätt upphöjda, icke-ulcerösa röda knölar. Den exakta patogenesen för EN är inte klarlagd, även om den tros vara resultatet av avsättning av immunkomplex i venolerna i septae i subkutant fett, vilket orsakar en neutrofil pannikulit. Även utan specifik terapi för ett orsakande tillstånd, löser EN utan behandling i de flesta fall.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
"Erythema nodosum" är en form av pannikulit (panniculitis) som kännetecknas av ömma röda knölar, 1–10 cm, förknippade med systemiska symtom inklusive feber, sjukdomskänsla och ledvärk. Knölar kan avta under en period av 2–6 veckor utan sårbildning eller ärrbildning. Erythema nodosum är associerat med infektioner, inklusive hepatit C, EBV och tuberkulos, graviditet, non-Hodgkin lymfom och cancer i bukspottkörteln.