Acne - Chunusi
☆ Katika matokeo ya 2022 ya Stiftung Warentest kutoka Ujerumani, kuridhika kwa watumiaji na ModelDerm kulikuwa chini kidogo kuliko na mashauriano ya matibabu ya simu yanayolipishwa.
Chunusi kwenye eneo la torso. Sehemu ya juu ya torso na nyuma ni maeneo ya kawaida ya acne.
References
Chunusi, hali ya kawaida ya ngozi nchini Merika, ni shida ya ngozi inayoendelea. Matibabu inalenga kushughulikia mambo makuu manne yanayochangia chunusi: utokaji mwingi wa sebum, mkusanyiko wa seli za ngozi, ukoloni wa chunusi za Propionibacterium, na kusababisha uvimbe. Retinoids ya juu husimamia vyema vidonda vya uchochezi na visivyo na uchochezi kwa kuzuia na kupunguza comedones wakati wa kushughulikia kuvimba. Peroksidi ya benzoyl, inapatikana kwenye duka, ni wakala wa kuua bakteria bila kukuza upinzani wa bakteria. Wakati antibiotics ya kichwa na ya mdomo hufanya kazi peke yake, kuchanganya na retinoids ya juu huongeza ufanisi wao. Kuongeza peroksidi ya benzoyl kwa tiba ya antibiotiki hupunguza hatari ya upinzani wa bakteria. Isotretinoin ya mdomo, iliyoidhinishwa kwa chunusi kali na mkaidi, inasimamiwa kupitia mpango wa iPLEDGE.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Matibabu ya kawaida ya chunusi ni pamoja na benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Antibiotics ya mdomo kwa muda mrefu imekuwa sehemu muhimu ya matibabu ya chunusi, haswa kwa kesi za wastani hadi kali. Zinafanya kazi vizuri zaidi zinapotumiwa pamoja na retinoid ya mada na BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin zote zimeonyesha ushahidi wa ufanisi.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Topical retinoids ni daima ilipendekeza kwa ajili ya kutibu chunusi. Unapotumia antibiotics ya kimfumo au ya juu, ni muhimu kuchanganya na peroxide ya benzoyl na retinoids, lakini kwa hadi wiki 12 tu. Isotretinoin imetengwa kwa ajili ya kesi kali za chunusi ambazo hazijajibu matibabu mengine. Ingawa kuna ushahidi fulani wa matibabu ya kimwili kama vile tiba ya leza na maganda ya kemikali, pamoja na mbinu za ziada kama vile sumu ya nyuki iliyosafishwa na baadhi ya vyakula, ufanisi wake bado hauna uhakika.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Tafiti nyingi zimeangalia jinsi vyakula mbalimbali vinavyoathiri chunusi kwa wagonjwa. Waligundua kuwa watu wenye chunusi wanaokula vyakula vyenye kiwango cha chini cha glycemic huwa na madoa machache ya chunusi ukilinganisha na wale wanaokula vyakula vyenye mzigo mkubwa wa glycemic. Maziwa pia yamejifunza kuhusiana na acne. Inaonekana kwamba baadhi ya protini katika maziwa inaweza kuchangia zaidi chunusi kuliko mafuta au maudhui ya jumla ya maziwa. Utafiti mwingine umezingatia asidi ya mafuta ya omega-3 na asidi ya γ-linoleic. Inapendekeza kwamba watu wenye chunusi wanaweza kufaidika kwa kula samaki zaidi na mafuta yenye afya ili kuongeza ulaji wao wa asidi hizi za mafuta. Tafiti za hivi majuzi kuhusu dawa za kuzuia chunusi zinaonyesha matokeo ya kuahidi, lakini utafiti zaidi unahitajika ili kuthibitisha matokeo haya ya mapema.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Katika jinsia zote, homoni zinazoitwa androjeni zinaonekana kuwa sehemu ya utaratibu wa msingi, kwa kusababisha kuongezeka kwa uzalishaji wa sebum. Sababu nyingine ya kawaida ni ukuaji wa kupindukia wa bakteria Cutibacterium acnes, ambayo iko kwenye ngozi.
Matibabu yanayopakwa moja kwa moja kwenye ngozi iliyoathirika, kama vile asidi azelaic, peroxide ya benzoyl, na asidi ya salicylic, hutumiwa kwa kawaida. Antibiotics na retinoids zinapatikana katika michanganyiko ambayo hutumiwa kwenye ngozi na kuchukuliwa kwa mdomo kwa ajili ya matibabu ya acne. Hata hivyo, upinzani dhidi ya antibiotics unaweza kuendeleza kutokana na tiba ya antibiotic. Aina kadhaa za dawa za kupanga uzazi zinaweza kusaidia kuzuia chunusi kwa wanawake. Matibabu ya mapema na ya ukali ya chunusi kwa kutumia isotretinoin inaweza kusaidia kupunguza shida ya muda mrefu kwa watu binafsi.
○ Matibabu
Gel ya Adapalene inaweza kutumika sana kwa sababu inakandamiza usiri wa sebum na ina athari ya kukandamiza urejesho wa chunusi. Gel ya Adapalene inaweza kuwasha ngozi ikiwa inatumiwa sana hapo awali. Peroxide ya benzoyl na asidi azelaic, kwa upande mwingine, inaweza kutumika kwenye maeneo ya kuvimba kwa acne kwa sababu husaidia kwa kuvimba. Kwa ujumla, matibabu ya muda mrefu ya mwezi 1 au zaidi inahitajika ili kuona athari.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction