Angiofibroma
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References
Cutaneous angiofibromas inaweza kuonekana katika sehemu mbalimbali za mwili. Kwenye uso, mara nyingi hujulikana kama papuli za nyuzi au sebaceum ya adenoma; kwenye uume, wanaitwa pearly penile papules ; chini ya msumari, zinaitwa periungual angiofibromas au uvimbe wa Koenen; na mdomoni, zinajulikana kama fibromas ya mdomo. Angiofibroma ya uso ni sifa kuu ya tuberous sclerosis (TS) , ugonjwa wa kurithi unaoathiri ngozi, figo, moyo, ubongo, na mapafu. Kawaida hukua usoni wakati wa utoto au utu uzima kwa watu walio na TS. Kuwa na angiofibroma tatu au zaidi ya uso au angiofibromas mbili au zaidi za periungual inachukuliwa kuwa muhimu katika kuchunguza TS. Zaidi ya hayo, angiofibroma nyingi za uso zinaweza kuwepo katika hali (multiple endocrine neoplasia type 1 (MEN-1) na Birt-Hogg-Dubé syndrome) . Pearly penile papules zinapatikana kwenye ukingo wa moyo na sulcus ya uume. Ni matuta yasiyo na uchungu yanayoonekana zaidi kwa wanaume ambao hawajatahiriwa.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
1) uso
Fibrous papule
2) uume
Pearly penile papule
3) chini ya ukucha au ukucha
Periungual angiofibroma