Lichen planus
https://en.wikipedia.org/wiki/Lichen_planus
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References
Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis 24672362 NIH
Lichen planus (LP) ni hali ya uchochezi ya muda mrefu ambayo huathiri zaidi watu wazima katika miaka yao ya kati. Inaweza kuonekana kwenye ngozi au utando wa mucous kama vile mdomo, uke, umio, kisanduku cha sauti na utando wa macho. LP huja kwa namna tofauti kulingana na jinsi vipele vinavyoonekana na mahali vinapoonekana. Uchunguzi unaonyesha kuwa aina fulani za LP, kama zile zinazoathiri umio au macho, zinaweza zisigunduliwe vya kutosha. Baadhi ya aina za LP, kama vile aina za haipatrofiki na mmomonyoko mdomoni, zinaweza kuwa nzito na kudumu kwa muda mrefu. Vipengele vingine kama vile dawa au kugusa vitu fulani vinaweza kusababisha upele unaofanana.
Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. LP can involve the skin or mucous membranes including the oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. It has different variants based on the morphology of the lesions and the site of involvement. The literature suggests that certain presentations of the disease such as esophageal or ophthalmological involvement are underdiagnosed. The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. LP can significantly affect the quality of life of patients as well. Drugs or contact allergens can cause lichenoid reactions as the main differential diagnosis of LP.
Lichen Planus 10865927Lichen planus ni hali ya ngozi inayoonyeshwa na mabaka ya rangi ya zambarau, yenye sehemu bapa ambayo inaweza kusababisha kuwashwa sana. Vidonda hivi vya ngozi vinaweza kusumbua, haswa vinapoathiri sana mdomo au sehemu za siri. Katika hali mbaya, oral lichen planus inaweza hata kuongeza hatari ya kupata aina ya saratani ya ngozi. Inaweza pia kuathiri ngozi ya kichwa na misumari. Ingawa sababu ya matukio mengi haijulikani, baadhi yanaweza kusababishwa na dawa fulani au maambukizi ya hepatitis C. Matibabu kwa kawaida huhusisha krimu kali kwa visa vilivyojanibishwa na steroidi za mdomo kwa zilizoenea zaidi.
Lichen planus is a skin condition marked by purplish, flat-topped bumps and patches that can cause intense itching. These skin lesions can be distressing, especially when they affect the mouth or genitals severely. In severe cases, oral lichen planus may even increase the risk of developing a type of skin cancer. It can also affect the scalp and nails. While the cause of most cases is unknown, some may be triggered by certain medications or hepatitis C infection. Treatment typically involves strong creams for localized cases and oral steroids for more widespread ones.
Oral lichen planus 32753462 NIH
Lichen planus ni hali ambapo mfumo wa kinga husababisha uvimbe, na kusababisha alama tofauti kwenye ngozi na utando wa mucous. Inathiri takriban 5% ya watu wazima, mara nyingi zaidi wanawake, na kawaida huanza karibu na umri wa kati. Ushiriki wa mdomo huonekana katika hadi 77% ya kesi, hasa zinazoathiri shavu la ndani. Ingawa watu wengine hawawezi kuhisi dalili zozote, wengine wanaweza kupata maumivu na kuwa na shida na vyakula fulani (k. M. , tindikali, viungo) au dawa ya meno.
Lichen planus is an immune-mediated inflammatory condition leading to characteristic lesions on skin and mucous membranes. It presents in up to 5% of the general adult population with a female predilection (2:1); the onset is most commonly in middle age. Up to 77% of patients with lichen planus have oral disease, with buccal mucosa the most common subsite. The oral lesions may be asymptomatic, although a subset of patients have pain and difficulty tolerating certain foods (e.g., acidic, spicy) and toothpaste.
Ili kuthibitisha utambuzi wa lichen planus ya ngozi, biopsy ya ngozi inaweza kufanyika. Direct immunofluorescence (DIF) inaweza kuwa muhimu kwa wagonjwa walio na vidonda vya ng'ombe ili kutofautisha hali kutoka kwa ugonjwa wa vesiculobullous wa autoimmune.