Taarifa zaidi ― Kiswahili

Limfangioma (Lymphangioma) pia inajulikana kama LM. Ni ugonjwa wa mishipa uliopo tangu kuzaliwa. Ni sifa ya ukuaji usio wa kawaida wa tishu za limfu kabla na baada ya kuzaliwa. Limfangioma huathiri takriban 1 kwa 2000 hadi 1 kwa 4000 watu, bila tofauti kubwa kati ya jinsia au rangi. Kesi nyingi (80‑90 %) hugunduliwa kabla ya umri wa miaka miwili. Dalili hutofautiana sana, kutoka kwa uvimbe wa ndani hadi upungufu mkubwa katika njia za limfatik (lymphatic), wakati mwingine husababisha uvimbe mkali unaojulikana kama elephantiasis. Kwa mfano, limfangioma kwenye shingo na uso inaweza kusababisha uvimbe wa uso, na katika hali mbaya, uharibifu. Inapoathiri ulimi, inaweza kusababisha ukukua kwa mfupa wa japo (mandibular overgrowth) na meno yaliyopangwa vibaya. Katika kinywa na shingo, inaweza kusababisha matatizo ya kupumua na dharura ya kutishia maisha. Machoni, inaweza kusababisha upotezaji wa maono, usogeo mdogo wa macho, kope za kulegea, na macho kufumba (exophthalmos). Kuhusika kwa viungo kunaweza kusababisha uvimbe na ukuaji usio wa kawaida wa tishu na mifupa. Uvimbe huu kwa kawaida hukua polepole, lakini maambukizo, mabadiliko ya homoni, au jeraha linaweza kusababisha ukuaji wa haraka, na hivyo kusababisha hatari za kutishia maisha zinazohitaji matibabu ya haraka.
Lymphangioma (lymphatic malformation, LM), a congenital vascular disease, is a low-flow vascular abnormality in lymphatic diseases that is characterized by excessive growth of lymphatic tissue during prenatal and postpartum development. The incidence rate of LM is ~1:2000–4000, with no variation between genders and races. Most patients (80–90%) are diagnosed before the age of two. The clinical manifestations of lymphangioma are quite different among patients, varying from local swelling leading to superficial mass to a large area of diffuse infiltrating lymphatic channel abnormalities resulting in elephantiasis. Cervicofacial LM can cause facial elephantiasis, and in some severe cases, it can lead to serious disfigurement of the face. Tongue LM can lead to mandibular overgrowth and occlusal asymmetry, and oral and cervical LM can cause obstructive acute respiratory distress and life-threatening situations. Orbital LM may lead to decreased vision, decreased extraocular muscle movement, ptosis and exophthalmos. LM of the extremities can trigger swelling or gigantism, accompanied by overgrowth of soft tissue and bones. LM usually grows slowly and steadily, but under certain conditions, such as infection, hormonal changes or trauma, it can grow explosively and become a life-threatening disease requiring immediate treatment.

Katika utafiti huu wa rejea, tulipitia watoto 24 ambao walikuwa na lymphangioma na walitibiwa kwa injeksheni ya bleomycin ya aqueous solution kuanzia Januari 1999 hadi Desemba 2004. Vidonda vingi (63%) vilipotea kabisa, 21% walipata majibu mazuri, na 16% hakujibu vizuri. Wagonjwa wawili walikuwa na uvimbe (tumour) ilirudi baadaye, na wengine wawili walikuwa na jipu katika mahali pa sindano. Kwa bahati nzuri, hatukuona matatizo mengine makubwa au madhara.
This is a retrospective study of 24 children diagnosed with lymphangioma and treated with intralesional injection of bleomycin aqueous solution from January 1999 to December 2004. Complete resolution was seen in 63% (15/24) of lesions, 21% (5/24) had good response and 16% (4/24) had poor response. The tumour recurred in 2 patients. Two other patients had abscess formation at the site of injection. No other serious complications or side effects were observed.

Aina kuu za lymphangioma ni kama ifuatavyo - lymphangioma circumscriptum, cavernous lymphangioma, cystic hygroma, lymphangioendothelioma. Hizi hufanya karibu 26 % ya uvimbe wa mishipa isiyo ya kawaida kwa watoto lakini sio kawaida kwa watu wazima. Lymphangioma circumscriptum, aina ya mara kwa mara, huonyesha mirija ya limfu ikichomoza kwenye ngozi, na kutengeneza vibovu (vesicles) zilizojaa umaji wazi sawa na kuzaa kwa chura, pamoja na uvimbe wa tishu. Kwa kawaida huonekana kwenye maeneo yenye mtandao tajiri wa limfu kama vile viungo, shina na makwapa. Mwanamke mwenye umri wa miaka 71 alikuja kwenye kliniki yetu akiwa na uvimbe unaoendelea wa miguu ya chini, matuta ya pinki ya labia (labial papules), kuwashwa (pruritus), na kiowevu cha limfu kinachovuja. Tuliondoa matuta yote kwa upasuaji kwa utaratibu unaoitwa labiectomy kuu ya pande mbili, tukisimama kwenye kiwango cha fascia cha Colles, huku tukihifadhi klitoris (clitoris) na fourchette.
The predominant types of lymphangioma are lymphangioma circumscriptum (LC), cavernous lymphangioma, cystic hygroma, and lymphangioendothelioma. These entities account for approximately 26% of benign vascular tumors in children but are rarer in adults. LC is the most common form of cutaneous lymphangioma and is characterized by superficial lymphatic ducts protruding through the epidermis. This condition results in clusters of clear fluid-filled vesicles resembling frog spawn and associated tissue edema. It is usually found on the proximal extremity, trunk, and axilla, which has an abundant lymphatic system. A 71-year-old female presented to our outpatient clinic with persistent edema of both lower limbs, clusters of pink labial papules, pruritus, and watery lymph oozing. We removed all the papules by performing bilateral major labiectomy down to the level of Colles' fascia, sparing the clitoris and fourchette.