Melasma
☆ Katika matokeo ya 2022 ya Stiftung Warentest kutoka Ujerumani, kuridhika kwa watumiaji na ModelDerm kulikuwa chini kidogo kuliko na mashauriano ya matibabu ya simu yanayolipishwa.
Ni hali ya kawaida inayozingatiwa kwa wanawake wa Asia katika miaka yao ya mapema ya 40. Kidonda kilichozunguka kwenye picha kiko karibu na lentigo badala ya melasma.
References
Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
Hivi majuzi, low-fluence Q-switched Nd:YAG (LFQSNY) laser imekuwa maarufu kwa kutibu melasma, haswa katika Asia. Kufupisha tafiti mbalimbali kulikuwa na changamoto, lakini LFQSNY inaonekana kuwa bora na salama kwa melasma ikilinganishwa na matibabu ya jadi. Hata hivyo, baadhi ya visa vya upunguzaji wa rangi yenye madoadoa vimeripotiwa kama athari ya LFQSNY, labda kutokana na nishati ya juu ya leza. Matumizi mabaya ya LFQSNY yanaweza pia kusababisha kuzidisha kwa rangi kutokana na uvimbe, hasa katika ngozi nyeusi.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Matatizo ya rangi ya rangi mara nyingi hupatikana katika huduma ya msingi. Aina za kawaida za matatizo ya hyperpigmentation ni pamoja na post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Melasma haiwezi kutatuliwa kwa matibabu ya laser kwa muda fulani, kwani ni ugonjwa ambao rangi ya rangi huzalishwa kwa kuendelea. Asidi ya Tranxenemic husaidia kuboresha kupunguza rangi.
○ Matibabu
Katika baadhi ya nchi (k.m. Japani, Korea), asidi ya mdomo ya tranexamic inapatikana kwenye kaunta na inafaa. Krimu ya melasma yenye asidi ya tranexamic na asidi azelaic inaweza kusaidia kwa kiasi.
Hydroquinone inaweza kutumika kimsingi kwa matibabu ya kuzidisha kwa rangi, lakini FDA ilisitisha bidhaa za OTC zilizo na hidrokwinoni kufikia 2020.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma