Poikiloderma
https://en.wikipedia.org/wiki/Poikiloderma
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References
Diagnosis and Differential Diagnosis of Poikiloderma of Civatte: A Dermoscopy Cohort Study 36892344 NIH
Poikiloderma of Civatte ni hali ya ngozi ya kawaida ambayo huonekana hasa kwenye shingo na uso, hasa kwa wanawake wenye ngozi ya urembo, waliomaliza hedhi. Inaonekana kama mchanganyiko wa mistari nyekundu, madoa meusi na ngozi nyembamba. Kwa kawaida, huathiri maeneo yaliyopigwa na jua, kama vile uso, shingo na kifua, lakini sio maeneo yenye kivuli. Poikiloderma of Civatte inaweza kuainishwa kulingana na vipengele vyake kuu: wekundu, madoa meusi, au mchanganyiko wa zote mbili. Sababu haswa haielewi kikamilifu, lakini vipengele kama vile kupigwa na jua, mabadiliko ya homoni, athari za manukato au vipodozi, na kuzeeka hufikiriwa kuchangia. Poikiloderma of Civatte huelekea kuwa mbaya polepole baada ya muda.
Poikiloderma of Civatte (PC) is a rather common benign dermatosis of the neck and face, mainly affecting fair-skinned individuals, especially postmenopausal females. It is characterized by a combination of a reticular pattern of linear telangiectasia, mottled hyperpigmentation and superficial atrophy. Clinically, it involves symmetrically sun-exposed areas of the face, the neck, and the V-shaped area of the chest, invariably sparing the anatomically shaded areas. Depending on the prevalent clinical feature, PC can be classified into erythemato-telangiectatic, pigmented, and mixed clinical types. The etiopathogenesis of PC is incompletely understood. Exposure to ultraviolet radiation, hormonal changes of menopause, contact sensitization to perfumes and cosmetics, and normal ageing have been incriminated. The diagnosis is usually clinical and can be confirmed by histology, which is characteristic, but not pathognomonic. The course is slowly progressive and irreversible, often causing significant cosmetic disfigurement.