Erythema nodosum - Эритемаи Гиреҳ
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Erythema nodosum намуди маъмултарини панникулит аст, ки бо гиреҳҳои сурхи дардовар хос аст, ки асосан дар пойҳои поён пайдо мешаванд. Сабаби дақиқи он номаълум боқӣ мемонад, аммо ба назар чунин мерасад, ки он аз вокуниши муболиға ба триггерҳои гуногун натиҷа медиҳад. Гарчанде ки пайдоиши он аксар вақт номуайян аст, пеш аз ташхис primary erythema nodosum дигар шароитҳои асосиро истисно кардан муҳим аст. Он метавонад фарорасии бемориҳои системавӣ ба монанди сироятҳо, илтиҳоб, саратон ё аксуламал ба доруҳоро нишон диҳад. Триггерҳои маъмул иборатанд аз strep infections, tuberculosis, sarcoidosis, Behçet's disease, inflammatory bowel disease, certain medications, pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis ба маҷмӯи гуногуни шароити илтиҳобӣ, ки ба бофтаи чарбуи зери пӯст таъсир мерасонанд, дахл дорад. Ин шароитҳо дар кӯдакон кам нестанд. Panniculitis метавонад ё мушкилоти асосӣ дар ҳолати системавӣ ё аксуламали дуюмдараҷаи омилҳо ба монанди сироят, ҷароҳат ё доруҳои муайян бошад. Сарфи назар аз сабаб, аксари намудҳои panniculitis аломатҳои шабеҳ доранд, аз ҷумла гиреҳҳои дардовар ва сурх дар зери пӯст.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , илтиҳоби қабати чарбуи зери пӯст, як ҳолати нодирест, ки одатан ҳамчун гиреҳ ё часбҳои варамшуда зоҳир мешаванд. Erythema nodosum (EN) намуди маъмултарин аст, ки аксар вақт бо омилҳои гуногун ба вуҷуд меоянд. Дар ҳоле ки тақрибан 55% ҳолатҳо сабаби равшан надоранд, ангезаҳои маъмул инфексияҳо, доруҳо, баъзе бемориҳо ба монанди саркоидоз ва бемориҳои илтиҳобии рӯда, ҳомиладорӣ ва саратон мебошанд. EN одатан дар наврасон ва ҷавонон, бештар дар духтарон пайдо мешавад. Он аксар вақт бо эҳсоси умумии беморӣ, ки аз як то се ҳафта давом мекунад, бо аломатҳо ба монанди табларза ва мушкилоти роҳҳои болоии нафаскашӣ пеш меояд. Сипас, гиреҳҳои сурх одатан дар паҳлӯҳои берунии дастҳо ва пойҳо пайдо мешаванд, ки боиси дард мешаванд. Сабаби дақиқи EN пурра фаҳмида нашудааст, аммо боварӣ дорад, ки он комплексҳои иммуниро дар рагҳои хурди хунравии қабати чарбу ҷалб мекунад, ки боиси илтиҳоб мегардад. Одатан, биопсия илтиҳобро дар қабати чарбу бе осеб ба рагҳои хун нишон медиҳад. Ҳатто бидуни табобати мушаххас барои сабабҳои аслӣ, EN аксар вақт худ аз худ ҳал мешавад. Ҳамин тавр, аксари беморон танҳо ба нигоҳубини дастгирӣ барои нишонаҳои худ ниёз доранд.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Erythema nodosum ба таври клиникӣ ташхис карда мешавад. Барои тасдиқи ташхиси номуайян биопсия гирифтан мумкин аст ва тавассути микроскопӣ тафтиш карда шавад. Барои истисно кардани бемориҳои шуш, бахусус саркоидоз ва сил бояд рентгени сина гузаронида шавад.