Angiofibroma
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References
Maaaring lumitaw ang Cutaneous angiofibromas sa iba't ibang bahagi ng katawan. Sa mukha, madalas silang kilala bilang fibrous papules o adenoma sebaceum; sa titi, sila ay tinatawag na pearly penile papules ; sa ilalim ng kuko, ang mga ito ay tinatawag na periungual angiofibromas o Koenen tumor; at sa bibig, ang mga ito ay tinutukoy bilang oral fibromas. Ang facial angiofibromas ay isang kilalang tampok ng tuberous sclerosis (TS) , isang minanang sakit na nakakaapekto sa balat, bato, puso, utak, at baga. Karaniwang nabubuo ang mga ito sa mukha sa panahon ng pagkabata o maagang pagtanda sa mga indibidwal na may TS. Ang pagkakaroon ng tatlo o higit pang facial angiofibromas o dalawa o higit pang periungual angiofibromas ay itinuturing na makabuluhan sa pag-diagnose ng TS. Bukod pa rito, maaaring magkaroon ng maraming facial angiofibromas sa mga kondisyon (multiple endocrine neoplasia type 1 (MEN-1) at Birt-Hogg-Dubé syndrome) . Pearly penile papules ay matatagpuan sa kahabaan ng coronal margin at sulcus ng ari ng lalaki. Ang mga ito ay paulit-ulit, walang sakit na mga bukol na mas karaniwang nakikita sa mga lalaking hindi tuli.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
1) mukha
Fibrous papule
2) titi
Pearly penile papule
3) sa ilalim ng kuko o kuko sa paa
Periungual angiofibroma