Melasma
☆ Sa 2022 na mga resulta ng Stiftung Warentest mula sa Germany, ang kasiyahan ng consumer sa ModelDerm ay bahagyang mas mababa kaysa sa mga bayad na konsultasyon sa telemedicine.
Ito ay isang karaniwang kondisyon na naobserbahan sa mga babaeng Asyano sa kanilang maagang 40s. Ang bilog na sugat sa larawan ay mas malapit sa lentigo kaysa sa melasma.
References
Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
Kamakailan, naging popular ang low-fluence Q-switched Nd:YAG (LFQSNY) laser para sa paggamot ng melasma, lalo na sa Asia. Ang pagbubuod ng magkakaibang pag-aaral ay mahirap, ngunit ang LFQSNY ay tila sa pangkalahatan ay epektibo at ligtas para sa melasma kumpara sa mga tradisyunal na therapy. Gayunpaman, ang ilang mga kaso ng mottled hypopigmentation ay naiulat bilang isang side effect ng LFQSNY, posibleng dahil sa mataas na laser energy. Ang agresibong paggamit ng LFQSNY ay maaari ding humantong sa hyperpigmentation mula sa pamamaga, lalo na sa mas madidilim na kulay ng balat.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Ang mga problema sa pigmentation ay madalas na matatagpuan sa pangunahing pangangalaga. Kasama sa mga karaniwang uri ng hyperpigmentation disorder ang post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Ang melasma ay hindi malulutas sa laser treatment para sa isang tiyak na tagal ng panahon, dahil ito ay isang sakit kung saan ang pigment ay patuloy na ginagawa. Ang tranxenemic acid ay nakakatulong upang mapabuti ang pigmentation.
○ Paggamot
Sa ilang bansa (hal. Japan, Korea), ang oral tranexamic acid ay available sa counter at epektibo. Ang melasma cream na may tranexamic acid at azelaic acid ay maaaring bahagyang nakakatulong.
Maaaring gamitin ang hydroquinone para sa paggamot ng hyperpigmentation, ngunit itinigil ng FDA ang mga produktong OTC na naglalaman ng hydroquinone noong 2020.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma