Urticaria pigmentosa
Ang Urticaria pigmentosa ay ang pinakakaraniwang anyo ng cutaneous mastocytosis. Ito ay isang bihirang sakit na sanhi ng labis na bilang ng mga mast cell sa balat na nagdudulot ng pantal o sugat kapag naiirita. Ang mga pulang o kayumangging batik ay madalas na nakikita sa balat, karaniwan sa paligid ng dibdib, noo, at likod. Ang mga mast cell na ito, kapag inis (hal. sa pamamagitan ng pagkuskos sa balat o pagkakalantad sa init), ay gumagawa ng sobrang dami ng histamine, na nag-uudyok ng isang reaksiyong alerdyi na humahantong sa mga pantal na nakalocalize sa lugar ng pangangati, kung minsan ay tinatawag na “Darier's sign”.
☆ Sa 2022 na mga resulta ng Stiftung Warentest mula sa Germany, ang kasiyahan ng consumer sa ModelDerm ay bahagyang mas mababa kaysa sa mga bayad na konsultasyon sa telemedicine.
Ito ay may posibilidad na mangyari sa katawan ng maliliit na bata.
relevance score : -100.0%
ReferencesAng Mastocytosis ay isang kondisyon kung saan may labis na mast cell, kadalasang matatagpuan sa iba't ibang bahagi ng katawan tulad ng balat, bone marrow, at digestive system. Ayon sa World Health Organization (WHO), ang cutaneous mastocytosis ay maaaring ikategorya sa tatlong pangunahing uri. Ang unang uri (mastocytomas) ay binubuo ng isang o ilang (≤3) lesyon. Ang pangalawang uri (urticaria pigmentosa) ay nagsasangkot ng maraming lesyon, karaniwang higit sa 10 ngunit mas mababa sa 100. Ang huling uri ay nagpapakita ng malawakang pagkakasangkot sa balat. Ang urticaria pigmentosa ay ang pinakakaraniwang anyo ng cutaneous mastocytosis sa mga bata, ngunit maaari rin itong mangyari sa mga matatanda. Karaniwan itong hindi nakakapinsalang kondisyon na kadalasang bumubuti sa panahon ng pagdadalaga. Hindi tulad ng pang‑adultong mastocytosis, ang urticaria pigmentosa ay bihirang makaapekto sa mga panloob na organo. Isang natatanging katangian ng urticaria pigmentosa ang posibilidad na magdulot ng maliliit, makati, mapula‑pula, kayumanggi, o dilaw‑dilaw na mga batik o sugat sa balat, na karaniwang tinatawag na pantal. Ang mga batik na ito ay karaniwang lumilitaw sa pagkabata at maaaring tumagal sa buong buhay.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Isang 6 na taong gulang na batang babae ang pumasok dahil may ilang madilim na kulay na mga batik na unang lumitaw sa kanyang anit at kalaunan ay kumalat sa mukha at katawan sa loob ng anim na buwan. Binanggit niya na ang mga batik ay tumataas, namumula, at nangangati kapag nilalapat ang presyon. Hindi siya nakaranas ng pamumula, pagsusuka, pagtatae, o hirap sa paghinga, at ang kanyang personal at pamilyang medikal na kasaysayan ay walang kaugnay na pahiwatig. Sa pisikal na pagsusuri, nakita namin ang maraming madilim na batik sa anit, noo, mukha, at leeg, pati na rin ang bahagyang nakataas na madilim na patak sa dibdib at likod. Ang bahagyang pagkuskos sa mga batik ay nagdulot ng pamamaga at pangangati sa loob ng 2 minuto, ngunit nawala ang mga sintomas matapos ang 15–20 minuto (Darier's sign).
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
