Grover disease - Grover Hastalığı
Grover Hastalığı (Grover disease), genellikle yaşlı erkeklerde gövdede aniden kaşıntılı kırmızı lekeler şeklinde ortaya çıkan bir durumdur.
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ReferencesGeçici akantolitik dermatoz olarak da bilinen Grover disease, çoğunlukla yaşlı beyaz erkeklerde vücudun üst kısmında sıvıyla dolu şişlikler şeklinde görülen bir döküntüdür. Sıklıkla kaşınır ancak uzun sürmez. Grover disease'da dört farklı doku değişikliği modeli vardır ve bu, kan kanseri gibi çeşitli hastalıklarla ilişkilendirilmiştir. Kendi kendine gelip gitme eğiliminde olduğundan takibi ve tedavisi zor olabilir. Grover disease sıklıkla diğer dermatolojik ve dermatolojik olmayan cilt rahatsızlıklarıyla ilişkilendirildiğinden, hematopoietik maligniteler de dahil olmak üzere eşlik eden diğer bozuklukların dışlanması önemlidir.
Grover disease, also known as transient acantholytic dermatosis, is a rash that appears as bumps filled with fluid on the upper body, mainly in older white men. It's often itchy but doesn't last long. There are 4 different patterns of tissue changes in Grover disease, and it has been linked to various illnesses, like blood cancers. It can be hard to track and treat because it tends to come and go on its own. Because Grover disease has been associated frequently with other dermatologic and nondermatologic skin conditions, to rule out other concomitant disorders, including hematopoietic malignancies is essential.
Grover disease, also known as transient acantholytic dermatosis, is a rash that appears as bumps filled with fluid on the upper body, mainly in older white men. It's often itchy but doesn't last long. There are 4 different patterns of tissue changes in Grover disease, and it has been linked to various illnesses, like blood cancers. It can be hard to track and treat because it tends to come and go on its own. Because Grover disease has been associated frequently with other dermatologic and nondermatologic skin conditions, to rule out other concomitant disorders, including hematopoietic malignancies is essential.
Bu rapor, son üç‑dört ayda göğsünde döküntü bulunan 80 yaşındaki beyaz bir hastada nadir bir Grover's disease vakasını tartışmaktadır. Hastanın yüksek tansiyon, yüksek kolesterol, diz artriti, kronik asit reflüsü, hızlı kalp atım hızı, geçmiş prostat kanseri ve huzursuz bacak sendromu öyküsü vardır. Başlangıçta vücudunun üst kısmında kaşıntılı, kırmızı ve dalgalı bir döküntü görülmüştür. Çeşitli krem ve losyonlar kullanılmasına rağmen semptomlarda belirgin bir iyileşme sağlanamamıştır. Dermatologla görüşüp cilt biyopsisi yaptırdıktan sonra Grover's disease tanısı konulmuştur. Ardından iki hafta boyunca steroid krem ile tedavi uygulanmıştır.
This case report details a rare case of Grover's disease in an 80-year-old Caucasian male complaining of a rash across his chest over the last three to four months. The patient has a past medical history of essential hypertension, hyperlipidemia, osteoarthritis of the knee, chronic gastroesophageal reflux disease (GERD), supraventricular tachycardia, status post prostate cancer, and restless legs syndrome. During his initial evaluation, he was found to have a pruritic, erythematous, papular rash most notably along his upper trunk and chest. The patient utilized multiple lotions, emollients, and anti-itch creams with minimal relief of his symptoms and presentation. Following a referral to Dermatology, a biopsy of the rash was conducted, which revealed intraepidermal acantholysis, the hallmark finding for a diagnosis of Grover's disease. Subsequently, he was treated with a topical triamcinolone acetonide 0.1% cream for 14 days.
This case report details a rare case of Grover's disease in an 80-year-old Caucasian male complaining of a rash across his chest over the last three to four months. The patient has a past medical history of essential hypertension, hyperlipidemia, osteoarthritis of the knee, chronic gastroesophageal reflux disease (GERD), supraventricular tachycardia, status post prostate cancer, and restless legs syndrome. During his initial evaluation, he was found to have a pruritic, erythematous, papular rash most notably along his upper trunk and chest. The patient utilized multiple lotions, emollients, and anti-itch creams with minimal relief of his symptoms and presentation. Following a referral to Dermatology, a biopsy of the rash was conducted, which revealed intraepidermal acantholysis, the hallmark finding for a diagnosis of Grover's disease. Subsequently, he was treated with a topical triamcinolone acetonide 0.1% cream for 14 days.
