Acne - Akne
☆ Germaniyaning 2022 yilgi Stiftung Warentest natijalariga ko'ra, iste'molchilarning ModelDermdan qoniqish darajasi pullik teletibbiyot maslahatlariga qaraganda bir oz pastroq bo'lgan.
Tana sohasidagi akne. Torso va orqa tomonning yuqori qismi akne paydo bo'lishining keng tarqalgan joylari hisoblanadi.
References
Qo'shma Shtatlardagi eng keng tarqalgan teri kasalligi bo'lgan akne - bu doimiy yallig'lanishli teri muammosi. Davolash akne paydo bo'lishiga yordam beradigan to'rtta asosiy omilni ko'rib chiqishga qaratilgan: ortiqcha yog' ishlab chiqarish, teri hujayralarining to'planishi, Propionibacterium acnes kolonizatsiyasi va natijada yallig'lanish. Topikal retinoidlar yallig'lanishni bartaraf etishda komedonlarning oldini olish va kamaytirish orqali yallig'lanishli va yallig'lanishsiz lezyonlarni samarali boshqaradi. Reçetesiz sotiladigan benzoil peroksid bakteritsid agenti bo'lib, bakterial qarshilikni kuchaytirmaydi. Mahalliy va og'iz antibiotiklari yolg'iz ishlayotgan bo'lsa-da, ularni topikal retinoidlar bilan birlashtirish ularning samaradorligini oshiradi. Antibiotik terapiyasiga benzoil peroksid qo'shilishi bakterial qarshilik xavfini kamaytiradi. Jiddiy va o'jar akne uchun tasdiqlangan og'iz izotretinoin iPLEDGE dasturi orqali qo'llaniladi.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Akne uchun keng tarqalgan topikal muolajalar benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, and sulfone agents ni o'z ichiga oladi. Og'iz orqali antibiotiklar uzoq vaqt davomida akne davolashning asosiy qismi bo'lib kelgan, ayniqsa o'rtacha va og'ir holatlarda. Ular topikal retinoid va BP bilan birgalikda qo'llanilganda yaxshi ishlaydi. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, and cephalexin hammasi samaradorlikni isbotladi.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Akne davolash uchun har doim topikal retinoidlar tavsiya etiladi. Tizimli yoki topikal antibiotiklardan foydalanganda, ularni benzoil peroksid va retinoidlar bilan birlashtirish muhim, lekin faqat 12 haftagacha. Isotretinoin boshqa muolajalarga javob bermagan og'ir akne holatlari uchun ajratilgan. Lazer terapiyasi va kimyoviy peeling kabi jismoniy muolajalar, shuningdek, tozalangan ari zahari va ba'zi parhezlar kabi qo'shimcha yondashuvlar uchun ba'zi dalillar mavjud bo'lsa-da, ularning samaradorligi hali ham noaniq.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Bir nechta tadqiqotlar turli xil ovqatlar bemorlarda akne paydo bo'lishiga qanday ta'sir qilishini ko'rib chiqdi. Ular glisemik yuki past bo'lgan ovqatlarni iste'mol qiladigan akne bilan og'rigan odamlarda glisemik yuki yuqori bo'lgan ovqatlarni iste'mol qiladiganlarga qaraganda kamroq akne dog'lari borligini aniqladilar. Sut mahsulotlari ham akne bilan bog'liq holda o'rganilgan. Ko'rinib turibdiki, sutdagi ba'zi oqsillar yog' yoki umumiy sut tarkibiga qaraganda akne paydo bo'lishiga ko'proq hissa qo'shishi mumkin. Boshqa tadqiqotlar omega-3 yog 'kislotalari va g-linoleik kislotaga qaratilgan. Bu shuni ko'rsatadiki, akne bilan og'rigan odamlar ushbu yog' kislotalarini iste'mol qilishni ko'paytirish uchun ko'proq baliq va sog'lom yog'larni iste'mol qilishlari mumkin. Akne uchun probiyotiklar bo'yicha so'nggi tadqiqotlar istiqbolli natijalarni ko'rsatadi, ammo bu dastlabki topilmalarni tasdiqlash uchun ko'proq tadqiqotlar talab etiladi.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Ikkala jinsda ham, androgenlar deb ataladigan gormonlar sebum ishlab chiqarishning ko'payishiga olib keladigan asosiy mexanizmning bir qismi bo'lib ko'rinadi. Yana bir keng tarqalgan omil - bu terida mavjud bo'lgan Cutibacterium acnes bakteriyasining haddan tashqari ko'payishi.
To'g'ridan-to'g'ri ta'sirlangan teriga qo'llaniladigan muolajalar, masalan, azelaik kislota, benzoil peroksid va salitsil kislotasi odatda qo'llaniladi. Antibiotiklar va retinoidlar teriga surtiladigan va akne davolash uchun og'iz orqali olinadigan formulalarda mavjud. Ammo antibiotik terapiyasi natijasida antibiotiklarga qarshilik rivojlanishi mumkin. Bir necha turdagi tug'ilishni nazorat qilish tabletkalari ayollarda akne paydo bo'lishining oldini olishga yordam beradi. Izotretinoin yordamida akneni erta va agressiv davolash odamlarda uzoq muddatli asoratlarni kamaytirish uchun foydali bo'lishi mumkin.
○ Davolash
Adapalen gelidan keng foydalanish mumkin, chunki u sebum sekretsiyasini bostiradi va akne qaytalanishini bostirish ta'siriga ega. Adapalen jeli dastlab juda ko'p qo'llanilsa, terini bezovta qilishi mumkin. Benzoil peroksid va azelaik kislota, aksincha, yallig'lanishli akne joylarida ishlatilishi mumkin, chunki ular yallig'lanishga yordam beradi. Umuman olganda, ta'sirni ko'rish uchun 1 oy yoki undan ko'proq uzoq muddatli davolanish kerak.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction