Erythema nodosum - Eritema Nodosum
☆ Germaniyaning 2022 yilgi Stiftung Warentest natijalariga ko'ra, iste'molchilarning ModelDermdan qoniqish darajasi pullik teletibbiyot maslahatlariga qaraganda bir oz pastroq bo'lgan.
Oyoqda og'riqli eritematoz tugun shaklida namoyon bo'ladi.
References
Erythema nodosum pannikulitning eng keng tarqalgan turi bo'lib, og'riqli qizil tugunlar bilan tavsiflanadi, asosan pastki oyoqlarda joylashgan. Uning aniq sababi noma'lumligicha qolmoqda, ammo bu turli xil qo'zg'atuvchilarga bo'rttirilgan javob natijasida paydo bo'lgan ko'rinadi. Uning kelib chiqishi ko'pincha noaniq bo'lsa-da, primary erythema nodosum tashxisini qo'yishdan oldin boshqa asosiy sharoitlarni istisno qilish kerak. Bu infektsiyalar, yallig'lanish, saraton yoki dori-darmonlarga reaktsiyalar kabi tizimli kasalliklarning boshlanishini ko'rsatishi mumkin. Umumiy triggerlarga strep infections, tuberculosis, sarcoidosis, Behçet's disease, inflammatory bowel disease, certain medications, and pregnancy kiradi.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis teri ostidagi yog 'to'qimalariga ta'sir qiluvchi turli xil yallig'lanish sharoitlarini bildiradi. Bolalarda bu holatlar kam uchraydi. Panniculitis tizimli holatdagi asosiy muammo yoki infektsiya, shikastlanish yoki ba'zi dorilar kabi omillarga ikkinchi darajali reaktsiya bo'lishi mumkin. Nima bo'lishidan qat'iy nazar, panniculitis ning ko'p turlari shunga o'xshash alomatlarni, shu jumladan teri ostidagi og'riqli, qizil nodullarni ko'rsatadi.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , teri ostidagi yog 'qatlamining yallig'lanishi, kamdan-kam uchraydigan holat bo'lib, odatda shishgan tugunlar yoki yamalar shaklida namoyon bo'ladi. Erythema nodosum (EN) eng keng tarqalgan turi bo'lib, ko'pincha turli omillar bilan qo'zg'atiladi. Taxminan 55% hollarda aniq sabab bo'lmasa-da, umumiy qo'zg'atuvchilarga infektsiyalar, dori-darmonlar, sarkoidoz va yallig'lanishli ichak kasalliklari, homiladorlik va saraton kabi ba'zi kasalliklar kiradi. EN odatda o'smirlar va yoshlarda, ko'pincha ayollarda paydo bo'ladi. Ko'pincha bir haftadan uch haftagacha davom etadigan umumiy kasallik hissi, isitma va yuqori nafas olish yo'llari bilan bog'liq muammolar bilan birga keladi. Keyin, odatda, qo'l va oyoqlarning tashqi tomonlarida og'riq keltiradigan qizil nodullar paydo bo'ladi. EN ning aniq sababi to'liq tushunilmagan, ammo u yallig'lanishga olib keladigan yog 'qatlamining kichik qon tomirlarida immun komplekslarini o'z ichiga oladi, deb ishoniladi. Odatda, biopsiya qon tomirlariga zarar bermasdan, yog 'qatlamida yallig'lanishni ko'rsatadi. Hatto asosiy sababni aniq davolashsiz ham, EN ko'pincha o'z-o'zidan hal qilinadi. Shunday qilib, ko'pchilik bemorlar o'zlarining alomatlari uchun faqat qo'llab-quvvatlovchi yordamga muhtoj.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Eritema nodosum klinik jihatdan tashxis qilinadi. Noaniq tashxisni tasdiqlash uchun biopsiya olinishi va mikroskopik tekshiruvdan o'tishi mumkin. O'pka kasalliklarini, xususan, sarkoidoz va silni istisno qilish uchun ko'krak qafasi rentgenogrammasini o'tkazish kerak.