Intraepithelial carcinoma (Bowen disease) - Intraepitelial Karsinoma (Bouen Kasalligi)
☆ Germaniyaning 2022 yilgi Stiftung Warentest natijalariga ko'ra, iste'molchilarning ModelDermdan qoniqish darajasi pullik teletibbiyot maslahatlariga qaraganda bir oz pastroq bo'lgan.
Oddiy holat ― Intraepitelial Karsinoma (Bouen Kasalligi) (Intraepithelial carcinoma (Bowen disease)) uzoq davom etadigan, qichimaydigan ekzema sifatida noto'g'ri tashxis qo'yilgan bo'lishi mumkin.
References
Bowen's disease (BD) - terining tashqi qatlamidan (epidermis) boshlanadigan teri saratonining bir turi. Bu ko'proq kavkazliklarda uchraydi va ko'pincha quyosh nuri tushadigan joylarda uchraydi, lekin u boshqa joylarda ham paydo bo'lishi mumkin. BD odatda bitta lezyon sifatida namoyon bo'ladi. BD ko'pincha teri saratonining yanada jiddiy turi rivojlanishidan oldin ogohlantiruvchi belgi sifatida ko'riladi. BD tashxisini qo'yish uchun shifokorlar odatda mikroskop (biopsiya) ostida to'qimalar namunalarini tekshirishga tayanadilar.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease asosan 60 yoshdan oshgan oq tanli odamlarga ta'sir qiladi. Asosiy xavf omillariga uzoq muddatli quyosh ta'siri, zaif immunitet, mishyak ta'siri va teri HPV infektsiyasi kiradi. 16, 18, 34 va 48 HPV shtammlari genital sohalarda Bowen kasalligi bilan bog'liq. Genital bo'lmagan holatlarda HPV ning ishtiroki unchalik aniq emas.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Odatda tananing har qanday joyida eritematoz, qichitqi yoki qobiqli hudud sifatida namoyon bo'ladi. Eng keng tarqalgan joy - pastki oyoqlar.
Kriyoterapiya, kuretaj, koteriya, fotodinamik terapiya yoki lezyonni kesish kabi turli xil davolash usullari bilan davolash mumkin.
○ Diagnoz va davolash
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy