Prurigo nodularis
☆ Germaniyaning 2022 yilgi Stiftung Warentest natijalariga ko'ra, iste'molchilarning ModelDermdan qoniqish darajasi pullik teletibbiyot maslahatlariga qaraganda bir oz pastroq bo'lgan.
References
Prurigo nodularis - bu, odatda, qo'l va oyoqlarning tashqi qismlarida joylashgan bir nechta qattiq bo'shliqlar va tugunlar bilan tavsiflangan uzoq davom etadigan teri kasalligi. Ushbu bo'g'inlarning rangi go'shtdan pushti ranggacha o'zgarishi mumkin va kuchli qichimadir. Ular har qanday yoshdagi odamlarga ta'sir qilishi mumkin va ko'pincha atopik dermatit kabi surunkali qichishishga olib keladigan boshqa teri kasalliklari bilan bog'liq. Davolash usullari orasida kuchli qichimaga qarshi dorilar, immunitet tizimiga ta'sir qiluvchi dorilar va asab tizimiga qaratilgan dorilar kiradi. Prurigo nodularisni boshqarish odatda uzoq muddatli terapiyani o'z ichiga oladi.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Davolash odatda ta'sirlangan hududga kremlar yoki steroid in'ektsiyalarini qo'llashni o'z ichiga oladi. Og'irroq yoki o'jar holatlarda yorug'lik terapiyasi yoki immunitet tizimini bostiradigan dorilar kabi muolajalar kerak bo'lishi mumkin. Talidomid va lenalidomid og'ir holatlar uchun tanlovdir, ammo ular jiddiy yon ta'sirga ega bo'lishi mumkin. Yangi davolash usullari (opioid receptor antagonists, neurokinin-1 receptor antagonists) prurigo nodularisni talidomid yoki lenalidomidga nisbatan kamroq yon ta'siri bilan davolashda va'da beradi.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Chronic prurigo - uzoq davom etadigan qichishish (6 haftadan ortiq) , tirnalgan teri lezyonlari va tez-tez tirnash xususiyati bilan tavsiflangan teri kasalligi. Bu terida neyroinflamasyon va fibrozni o'z ichiga oladi.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Prurigo nodularis - bu qichiydigan tugunlar bilan ajralib turadigan uzoq davom etadigan teri muammosi. Biz bunga nima sabab bo'lganini aniq bilmaymiz, ammo qichishish siklida immunitet va asab muammolari rol o'ynaydi. Hozirda AQSh FDA tomonidan maxsus prurigo nodularis uchun tasdiqlangan davolash usullari mavjud emas.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
○ Davolash ― OTC dori vositalari
Shikastlanish joyini sovun bilan yuvish umuman yordam bermaydi va uni yomonlashtirishi mumkin. OTC steroid malhamlari simptomlarni engillashtirishga yordam beradi, ammo ular odatda yaxshilash uchun bir necha hafta davomida qo'llanilishi kerak. Antigistaminlarni qabul qilishni davom ettirish ham qichishishni bartaraf etishga yordam beradi.
#OTC steroid ointment
#OTC antihistamine
○ Davolash
#Intralesional triamcinolone injection