Acne - Amabalahttps://en.wikipedia.org/wiki/Acne
Amabala (Acne) yenzeka kwiiseli zolusu ezifileyo kunye neoyile evela kwiifollicle zeenwele ezivale ulusu. Iimpawu eziqhelekileyo zesimo ziquka amabala amnyama okanye amhlophe, amaqhakuva, kunye nesikhumba esinamafutha. Ichaphazela kakhulu ulusu olunenani eliphezulu lamadlala e-oyile, kubandakanywa ubuso, indawo ephezulu yesifuba, kunye nomqolo. I-acne ixhaphakile ekufikiseni kwaye ichaphazela i-80-90% yolutsha kumazwe aseNtshona. Olunye uluntu lwasemaphandleni luchaza amazinga aphantsi amaqhakuva kunalawo aphuhlileyo.

Kuzo zombini izini, iihomoni ezibizwa ngokuba yi-androgens zibonakala ziyinxalenye yendlela esisiseko, ngokubangela ukwanda kwemveliso ye-sebum. Enye into eqhelekileyo kukukhula okugqithisileyo kwe-bacterium Cutibacterium acnes, ekhoyo eluswini.

Unyango olusetyenziswa ngokuthe ngqo kulusu oluchaphazelekayo, olufana ne-azelaic acid, i-benzoyl peroxide, kunye ne-salicylic acid, ziqhele ukusetyenziswa. I-Antibiotics kunye ne-retinoids ziyafumaneka kwiifom ezisetyenziselwa ulusu kwaye zithathwe ngomlomo ukwenzela unyango lwe-acne. Nangona kunjalo, ukuxhathisa kwi-antibiotics kunokuvela ngenxa yonyango lwe-antibiotic. Iintlobo ezininzi zeepilisi zokulawula ukuzalwa zinokunceda ukukhusela i-acne kubasetyhini. Unyango lwakwangoko kunye nolunya lwe-acne usebenzisa i-isotretinoin lunokuba luncedo ekunciphiseni ingxaki yexesha elide kubantu.

Unyango
Ijeli ye-Adapalene ingasetyenziselwa ngokubanzi kuba icinezela imfihlo ye-sebum kwaye inefuthe lokunciphisa ukuphindaphinda kwe-acne. Ijeli ye-Adapalene inokucaphukisa ulusu ukuba kuninzi kusetyenziswe ekuqaleni. I-Benzoyl peroxide kunye ne-azelaic acid, ngakolunye uhlangothi, ingasetyenziselwa kwiindawo ezivuthayo ze-acne kuba zinceda ngokuvuvukala. Ngokuqhelekileyo, unyango olude lwenyanga ye-1 okanye ngaphezulu lufunekayo ukuze ubone umphumo.

#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream

#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction
☆ Kwiziphumo zika-2022 ze-Stiftung Warentest ezivela eJamani, ukwaneliseka kwabathengi ngeModelDerm bekungaphantsi kancinci kunokubonisana nge-telemedicine ehlawulweyo.
  • I-Acne kwindawo ye-torso. Inxalenye ephezulu ye-torso kunye nomqolo yimimandla eqhelekileyo ye-acne.
  • Amaqhakuva esidleleni.
  • I-Acne ingenzeka ngasemva. Ukuba i-acne ivela ngequbuliso ngokubanzi kumqolo, drug eruption inokuqwalaselwa.
  • Amaqhakuva ebunzi. I-acne ebusheni idla ngokuqala ngebunzi.
  • Embindini womfanekiso, i-comedone emhlophe, engabonakaliyo ibonwa.
References Diagnosis and treatment of acne 23062156
I-acne, eyona meko yolusu ixhaphakileyo e-United States, yingxaki yolusu eqhubekayo yokudumba. Unyango lujolise ekujonganeni nezinto ezine eziphambili ezinegalelo kwi-acne: ukuveliswa kwe-sebum ngokugqithisileyo, ukwakhiwa kweeseli zesikhumba, i-Propionibacterium acnes colonization, kunye nesiphumo sokudumba. I-retinoids ye-topical ilawula ngokufanelekileyo zombini izilonda ezivuthayo kunye nezingadumbanga ngokuthintela kunye nokunciphisa i-comedones ngelixa ujongene nokuvuvukala. I-Benzoyl peroxide, ekhoyo kwi-counter-counter, i-agent ye-bactericidal ngaphandle kokukhuthaza ukuxhathisa kwebhaktheriya. Ngelixa i-antibiotics ye-topical kunye neyomlomo isebenza yodwa, ukudibanisa kunye ne-retinoids ye-topical kwandisa ukusebenza kwabo. Ukongeza i-benzoyl peroxide kunyango lokubulala iintsholongwane kwehlisa umngcipheko wokunganyangeki kwebhaktiriya. I-isotretinoin yomlomo, evunyiweyo ye-acne enzima kunye nenkani, ilawulwa ngeprogram ye-iPLEDGE.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
 Guidelines of care for the management of acne vulgaris 26897386
Unyango oluqhelekileyo lwamaqhakuva lubandakanya benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. I-antibiotics yomlomo kudala iyinxalenye ephambili yonyango lwe-acne, ngakumbi kwiimeko ezimodareyitha ukuya kwezinzima. Zisebenza kakuhle xa zisetyenziswa ecaleni kwe-retinoid ye-topical kunye ne-BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin zonke zibonise ubungqina bokusebenza.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
 Acne Vulgaris: Diagnosis and Treatment 31613567
I-retinoids yezihloko zihlala zinconywa ukunyanga i-acne. Xa usebenzisa i-systemic okanye i-antibiotics, kubalulekile ukuba udibanise ne-benzoyl peroxide kunye ne-retinoids, kodwa kuphela ukuya kwiiveki ezili-12. Isotretinoin igcinelwe iimeko ezinzima zamaqhakuva angakhange aphendule kolunye unyango. Ngelixa kukho ubungqina bonyango olufana nonyango lwelaser kunye namaxolo ekhemikhali, kunye neendlela ezihambelanayo ezifana netyhefu yenyosi ecocekileyo kunye nokutya okuthile, ukusebenza kwabo akukaqinisekwa.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
 Effects of Diet on Acne and Its Response to Treatment 32748305 
NIH
Izifundo ezininzi ziye zajonga indlela ukutya okwahlukileyo okuchaphazela ngayo i-acne kwizigulane. Baye bafumanisa ukuba abantu abane-acne abadla ukutya kunye nomthwalo ophantsi we-glycemic bavame ukuba neendawo ezincinci ze-acne xa kuthelekiswa nabatya ukutya okunomthwalo ophezulu we-glycemic. Imveliso yobisi nayo iye yaphononongwa ngokunxulumene namaqhakuva. Kubonakala ngathi iiproteni ezithile ezisebisini zinokufaka isandla ngakumbi kwi-acne kunamafutha okanye umxholo wobisi ngokubanzi. Olunye uphando lujolise kwi-omega-3 fatty acids kunye ne-γ-linoleic acid. Icebisa ukuba abantu abane-acne banokuzuza ngokutya iintlanzi ezininzi kunye neeoyile ezisempilweni ukunyusa ukutya kwabo kwezi acid ezinamafutha. Uphononongo lwakutsha nje malunga ne-probiotics ye-acne lubonisa iziphumo ezithembisayo, kodwa uphando oluninzi luyafuneka ukuze kuqinisekiswe ezi ziphumo zakwangoko.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.