Intraepithelial carcinoma (Bowen disease) - I-Intraepithelial Carcinoma (Isifo Se-Bowen)
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Kwiziphumo zika-2022 ze-Stiftung Warentest ezivela eJamani, ukwaneliseka kwabathengi ngeModelDerm bekungaphantsi kancinci kunokubonisana nge-telemedicine ehlawulweyo.
Kwiziphumo zika-2022 ze-Stiftung Warentest ezivela eJamani, ukwaneliseka kwabathengi ngeModelDerm bekungaphantsi kancinci kunokubonisana nge-telemedicine ehlawulweyo.
Imeko eqhelekileyo ― I-Intraepithelial Carcinoma (Isifo Se-Bowen) (Intraepithelial carcinoma (Bowen disease)) inokungafunyaniswanga njenge-eczema ehlala ixesha elide, engarhawuzeli.
relevance score : -100.0%
ReferencesBowen's disease (BD) luhlobo lomhlaza wolusu oluqala kumphandle wolusu (epidermis). Iyonakele kakhulu phakathi kwabantu abamhlophe kwaye ihlala isenzeka kwiindawo ezichache elangeni, kodwa inokuvela nakwezinye iindawo. I-BD ibonakala njengesilonda esisodwa. I-BD isoloko ibonwa njengophawu lwesilumkiso phambi kokuba kuvele uhlobo olubi kakhulu lomhlaza wolusu (squamous cell carcinoma). Ukuxilonga i-BD, oogqirha bahlala bexhomekeke ekuhloleni iisampulu zezicubu phantsi kwe-microscope (biopsy).
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease ikakhulu ichaphazela abantu abamhlophe abaneminyaka engaphezu kwama-60. Imiba ephambili yomngcipheko ibandakanya ukuba sesichengeni selanga (sun exposure) ixesha elide, ubuthathaka (immunosuppression), ukuvezwa kwe-arsenic (arsenic exposure), kunye nosulelo lwe-HPV yesikhumba (cutaneous HPV infection). Iintlobo ze-HPV 16, 18, 34, kunye ne-48 zinxulunyaniswa nesifo sika-Bowen kwiindawo zangasese (genital sites). Ukubandakanyeka kwe-HPV kwiimeko ezingezizo ezesini akucacanga kangako.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Ngokuqhelekileyo ibonakala njengendawo ebomvu (erythematous), ene‑scaly okanye e‑crusty (crusted) naphi na emzimbeni. Indawo eqhelekileyo yimilenze ephantsi (lower legs).
Iyaphulukiswa ngeendlela ezahlukeneyo zonyango ezifana ne‑cryotherapy, curettage, i‑cautery, unyango lwe‑photodynamic (photodynamic therapy), okanye ukukhutshwa kwesilonda (excision).
○ Uxilongo kunye noNyango
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy