A neurofibroma is a benign nerve-sheath tumor in the peripheral nervous system. In 90% of cases, they are found as stand-alone tumors, while the remainder are found in persons with neurofibromatosis type I (NF1), an autosomal-dominant genetically inherited disease. They can result in a range of symptoms from physical disfiguration and pain to cognitive disability.
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Neurofibromas zizidumba ezixhaphakileyo ezifumaneka kwimithambo‑luvo. Ngokuqhelekileyo, zikhangeleka njengamaqhuma athambileyo esikhumbeni okanye amaqhuma amancinci ngaphantsi kwawo. Zikhula zisuka kwi‑endoneurium kunye nezicubu ezidibeneyo ezijikeleze i‑peripheral nerve sheaths. Neurofibromas are the most prevalent benign peripheral nerve sheath tumor. Often appearing as a soft, skin-colored papule or small subcutaneous nodule, they arise from endoneurium and the connective tissues of peripheral nerve sheaths.
i-neurofibroma (neurofibroma) ingaba phakathi kwe‑2 ukuya kwi‑20 mm ububanzi, ithambile, i‑flaccid, kwaye ibonakala ngombala ophuzi‑mlovu. I‑biopsy ingasetyenziselwa ukuxilongwa kwe‑histopathology.
i-neurofibroma (neurofibroma) ngokuqhelekileyo iqala ukuvela kwiminyaka yeshumi elinanye ukuya kweshumi elinesihlanu yobudala, kwaye ivame ukukhula emva kokufika. Kubantu abanegciwane le‑Neurofibromatosis Type I, i‑neurofibroma iyaqhubeka nokwanda ngobuninzi kunye nobukhulu ebantwini abadala.