Syphilis - Igcushuwa
☆ Kwiziphumo zika-2022 ze-Stiftung Warentest ezivela eJamani, ukwaneliseka kwabathengi ngeModelDerm bekungaphantsi kancinci kunokubonisana nge-telemedicine ehlawulweyo.
Chancres ― primary syphilitic usulelo ngu Treponema pallidum
References
Igcushuwa sisifo esosulela ngesondo esibangelwa yintsholongwane iTreponema pallidum. Kolu phononongo, sigxile kwizigulane ezingama-57 ezineminyaka eyi-18-68 ezinegcushuwa yesibini.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Igcushuwa lusulelo lwebhaktiriya olubangelwa yiTreponema pallidum. Iyakwazi ukulinganisa izifo ezahlukeneyo, izuze igama lesidlaliso great imitator. I-Syphilis isachaphazela izigidi kwihlabathi jikelele kodwa inokunyangwa ngokufanelekileyo ngepenicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum ibangela igcushuwa ngokwabelana ngesondo okanye ukusuka kumama ukuya kusana ngexesha lokukhulelwa. Nangona kukho iimvavanyo ezilula zokuyixilonga kunye nonyango ngodubulo lwepenicillin olusebenza ixesha elide lusebenza kakuhle, igcushuwa iba yingxaki enkulu kwakhona kwihlabathi jikelele. Oku kuyinyani ngakumbi kumadoda abelana ngesondo namadoda (MSM) kumazwe anemivuzo ephezulu kunye nephakathi. Ngelixa amanye amazwe anengeniso ephantsi aye ahlangabezana neenjongo ze-WHO zokunqanda ukusuleleka kwegcushuwa ukusuka kumama ukuya kusana, kukho ukonyuka okuxhalabisayo kwegcushuwa phakathi kwe-MSM ene-HIV.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Isibindi Esandisiweyo: Oku kudla ngokufunyanwa kwaye kunokwenzeka ecaleni kodakada olwandisiweyo. Ukuphonononga i-biopsy yesibindi phantsi kwe-darkfield microscopy inokubonisa ubukho be-spirochete. Iimvavanyo zokusebenza kwesibindi zinokubonisa ukungaqhelekanga. (2) Ukutyhelwa kolusu (I-Jaundice) : Ukuba umntu ubonisa i-jaundice kuxhomekeke kwindlela esichaphazeleka ngayo isibindi. (3) Impumlo evuzayo: Idla ngokuba luphawu lokuqala, ngokuqhelekileyo kwiveki yokuqala emva kokuzalwa. (4) Ukuvuvukala kwe-Lymph Nodes: Ukuvuvukala ngokubanzi kwee-lymph nodes, ngokuqhelekileyo kungenabuhlungu, kuqhelekile. (5) Irhashalala yolusu: Irhashalala idla ngokuvela kwiveki enye okanye ezimbini emva kwempumlo. Unokubona amabala amancinci abomvu okanye apinki ngasemva, iimpundu, amathanga, kunye neenyawo zeenyawo. Le rhashalala inokuqhubela phambili ekuxobeni kunye nokuqweqwedisa.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Uxilongo kunye noNyango
I-VDRL kunye ne-RPR ingasetyenziselwa ukuqinisekisa usulelo lwamva nje kunye nesikrini segcushuwa. Uvavanyo lwe-FTA-ABS luvavanyo oluthe ngqo ngakumbi kwaye lunokusetyenziswa ukujonga imbali yosulelo lwangaphambili. Ipenicillin isetyenziselwa ukunyanga igcushuwa.