Urticariahttps://en.wikipedia.org/wiki/Hives
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References Acute and Chronic Urticaria: Evaluation and Treatment 28671445I-Urticaria, edla ngokubonakala ngokurhawuzelelwa ngamavili kwaye ngamanye amaxesha ukudumba kwesikhumba esinzulu, ilawulwa ngokunqanda izinto ezibangela ukuba zikwaziwe. Unyango oluphambili lubandakanya isizukulwana sesibini i-antihistamines ye-H1, enokuthi ilungelelaniswe kwiidosi eziphezulu xa kufuneka. Ukongezelela, amanye amayeza afana nesizukulwana sokuqala se-H1 antihistamines, i-H2 antihistamines, i-leukotriene receptor antagonists, i-antihistamine enamandla, kunye neekhosi ezimfutshane ze-corticosteroids zingasetyenziswa kunye. Kwiimeko eziqhubekayo, ukuthunyelwa kwiingcali zolunye unyango olufana ne-omalizumab okanye i-cyclosporine inokuqwalaselwa.
Urticaria, often characterized by itchy wheals and sometimes swelling of the deeper skin layers, is typically managed by avoiding triggers, if known. The primary treatment involves second-generation H1 antihistamines, which can be adjusted to higher doses if needed. Additionally, other medications like first-generation H1 antihistamines, H2 antihistamines, leukotriene receptor antagonists, potent antihistamines, and short courses of corticosteroids may be used alongside. For persistent cases, referral to specialists for alternative therapies like omalizumab or cyclosporine may be considered.
Urticaria and Angioedema: an Update on Classification and Pathogenesis 28748365 Chronic Urticaria 32310370 NIH
Second-generation H1-antihistamines (e.g., cetirizine, loratadine, fexofenadine), Omalizumab, Ciclosporin, and short courses only of systemic corticosteroids
Angioedema 30860724 NIH
Angioedema kukudumba okungawushiyiyo umngxuma xa ucinezelwe, okwenzeka kumaleko angaphantsi kwesikhumba okanye kwimifinya. Ngokuqhelekileyo ichaphazela iindawo ezifana nobuso, imilebe, intamo, kunye nemilenze, kunye nomlomo, umqala kunye namathumbu. Iba yingozi xa ichaphazela umqala, inokubangela ukuba imeko esongela ubomi.
Angioedema is non-pitting edema that involves subcutaneous and/or submucosal layers of tissue that affects the face, lips, neck, and extremities, oral cavity, larynx, and/or gut. It becomes life-threatening when it involves the larynx.
Uthintelo kukunqanda nantoni na ebangela imeko. Unyango luqhelekile ngee-antihistamines ezifana ne-diphenhydramine kunye ne-ranitidine. Kwiimeko ezinzima, i-corticosteroids okanye i-leukotriene inhibitors nayo ingasetyenziswa. Ukugcina ubushushu bendalo bupholile kuluncedo okwexeshana. Kwiimeko ezihlala ngaphezu kweeveki ezintandathu ii-immunosuppressants ezifana ne-cyclosporin zingasetyenziswa.
Sisifo esiqhelekileyo njengoko malunga ne-20% yabantu abachaphazelekayo. Iimeko ze-acute urticaria zenzeka ngokulinganayo kumadoda nabasetyhini ngelixa iimeko zexesha elide zixhaphake kakhulu kwabasetyhini. Iimeko ze-acute urticaria zixhaphake kakhulu phakathi kwabantwana ngelixa iimeko zexesha elide zixhaphake kakhulu phakathi kwabo baneminyaka ephakathi. Ukuba ihlala ngaphezu kweenyanga ezi-2, ihlala iminyaka kwaye ihambe.
○ Unyango ― OTC Amachiza
I-urticaria ye-acute ihlala ixazulula ngaphakathi kweveki, kodwa i-urticaria engapheliyo inokuhlala iminyaka nangona uninzi lwabo luhamba ngexesha elithile. Kwimeko ye-urticaria engapheliyo, kucetyiswa ukuba uthathe i-antihistamine rhoqo kwaye ulinde ukuba ihambe yodwa.
OTC antihitamines. I-Cetirizine okanye i-levocetirizine zisebenza ngakumbi kune-fexofenadine kodwa zikwenza wozele.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
Kwi-urticaria engapheliyo, i-antihistamine engapheliyo njenge-fexofenadine ikhethwayo.
#Fexofenadine [Allegra]
#Diphenhydramine [Benadryl]
#Loratadine [Claritin]