Acne - Irorẹ
https://en.wikipedia.org/wiki/Acne
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References
Diagnosis and treatment of acne 23062156Irorẹ, ipo awọ ti o wọpọ julọ ni Amẹrika, jẹ iṣoro awọ iredodo ti o tẹsiwaju. Itọju ni ifọkansi lati koju awọn ifosiwewe akọkọ mẹrin ti o ṣe idasi si irorẹ: iṣelọpọ sebum ti o pọ ju, iṣelọpọ sẹẹli awọ ara, Propionibacterium acnes colonization, ati iredodo ti o yọrisi. Awọn retinoids ti agbegbe ni imunadoko ni iṣakoso mejeeji iredodo ati awọn ọgbẹ ti kii-iredodo nipa idilọwọ ati idinku awọn comedones lakoko ti o n sọrọ iredodo. Benzoyl peroxide, ti o wa lori-counter, jẹ oluranlowo kokoro-arun lai ṣe igbega resistance kokoro-arun. Lakoko ti awọn oogun apakokoro ti agbegbe ati ti ẹnu ṣiṣẹ nikan, apapọ wọn pẹlu awọn retinoids ti agbegbe ṣe imunadoko wọn. Ṣafikun benzoyl peroxide si itọju ailera apakokoro dinku eewu ti resistance kokoro-arun. Isotretinoin ẹnu, ti a fọwọsi fun irorẹ lile ati agidi, ni a nṣakoso nipasẹ eto iPLEDGE.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Guidelines of care for the management of acne vulgaris 26897386Awọn itọju agbegbe ti o wọpọ fun irorẹ pẹlu benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Awọn oogun aporo ẹnu ti pẹ ti jẹ apakan pataki ti itọju irorẹ, paapaa fun iwọntunwọnsi si awọn ọran lile. Wọn ṣiṣẹ dara julọ nigbati a lo lẹgbẹẹ retinoid ti agbegbe ati BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin ti gbogbo han eri ti ndin.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Acne Vulgaris: Diagnosis and Treatment 31613567Awọn retinoids ti agbegbe ni a ṣe iṣeduro nigbagbogbo fun atọju irorẹ. Nigbati o ba nlo awọn oogun apakokoro tabi ti agbegbe, o ṣe pataki lati darapo wọn pẹlu benzoyl peroxide ati retinoids, ṣugbọn fun ọsẹ mejila nikan. Isotretinoin wa ni ipamọ fun awọn ọran lile ti irorẹ ti ko dahun si awọn itọju miiran. Lakoko ti awọn ẹri diẹ wa fun awọn itọju ti ara bii itọju ailera laser ati awọn peeli kemikali, bakanna bi awọn isunmọ ibaramu gẹgẹbi majele oyin mimọ ati awọn ounjẹ kan, imunadoko wọn tun jẹ aidaniloju.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Effects of Diet on Acne and Its Response to Treatment 32748305 NIH
Ọpọlọpọ awọn ijinlẹ ti wo bii awọn ounjẹ oriṣiriṣi ṣe ni ipa lori irorẹ ni awọn alaisan. Wọn rii pe awọn eniyan ti o ni irorẹ ti o jẹ ounjẹ pẹlu iwuwo kekere glycemic ṣọ lati ni awọn aaye irorẹ diẹ ni akawe si awọn ti o jẹ ounjẹ pẹlu iwuwo glycemic giga. Ibi ifunwara tun ti ṣe iwadi ni ibatan si irorẹ. O dabi pe awọn ọlọjẹ kan ninu wara le ṣe alabapin diẹ sii si irorẹ ju ọra tabi akoonu ifunwara lapapọ. Iwadi miiran ti dojukọ lori omega-3 fatty acids ati γ-linoleic acid. O ni imọran pe awọn eniyan ti o ni irorẹ le ni anfani lati jijẹ diẹ sii ẹja ati awọn epo ti o ni ilera lati mu alekun wọn ti awọn acids fatty wọnyi pọ si. Awọn ijinlẹ aipẹ lori awọn probiotics fun irorẹ fihan awọn abajade ti o ni ileri, ṣugbọn a nilo iwadii diẹ sii lati jẹrisi awọn awari ibẹrẹ wọnyi.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Ninu awọn obinrin mejeeji, awọn homonu ti a pe ni androgens han lati jẹ apakan ti ilana ti o wa ni ipilẹ, nipa nfa iṣelọpọ pọ si ti sebum. Ohun miiran ti o wọpọ ni idagba ti o pọju ti kokoro-arun Cutibacterium acnes, eyiti o wa lori awọ ara.
Awọn itọju ti a lo taara si awọ ara ti o kan, gẹgẹbi azelaic acid, benzoyl peroxide, ati salicylic acid, ni a lo nigbagbogbo. Awọn egboogi ati awọn retinoids wa ni awọn ilana ti a lo si awọ ara ti a fi ẹnu mu fun itọju irorẹ. Sibẹsibẹ, resistance si awọn oogun aporo le dagbasoke bi abajade ti itọju aporo aporo. Orisirisi awọn oogun iṣakoso ibi le ṣe iranlọwọ lati dena irorẹ ninu awọn obinrin. Itọju ibẹrẹ ati ibinu ti irorẹ nipa lilo isotretinoin le ṣe iranlọwọ lati dinku ilolu igba pipẹ lori awọn eniyan kọọkan.
○ Itọju
Geli Adapalene le ṣee lo ni ibigbogbo nitori pe o npa yomijade ti sebum ati pe o ni ipa ti didasilẹ awọn atunwi irorẹ. Geli Adapalene le binu awọ ara ti o ba lo pupọ ni ibẹrẹ. Benzoyl peroxide ati azelaic acid, ni apa keji, le ṣee lo lori awọn aaye irorẹ ti o ni ipalara nitori pe wọn ṣe iranlọwọ pẹlu igbona. Ni gbogbogbo, itọju igba pipẹ ti oṣu 1 tabi diẹ sii ni a nilo lati rii ipa kan.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction