Alaye siwaju sii ― Yoruba

Arabinrin kan ti o jẹ ọmọ ọdun 26 wa si ile-iwosan wa ti n kerora ti rirun yun lori awọn ẹsẹ rẹ ti o ti ni fun ọdun 10. Pelu lilo awọn ipara sitẹriọdu ati ipara tazarotene, sisu ko dara. O ko ni eyikeyi itan idile ti o yẹ. Nígbà tí a yẹ̀ ẹ́ wò, a rí àwọn àwọ̀tẹ́lẹ̀ tí ó gbé sókè, tí wọ́n gún ní iwájú ẹsẹ̀ rẹ̀, tí ó bá àìsàn kan tí a ń pè ní lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.

Lichen Amyloidosis jẹ ipo awọ ti o ṣọwọn ti o ni asopọ pẹlu nyún itẹramọṣẹ ti idi aimọ. Nigbagbogbo o fihan bi awọn iṣupọ ti dide, awọn abulẹ ti ko ni awọ lori awọn ita ti awọ ara. Lichen Amyloidosis maa farahan ninu awọn eniyan ti o wa ni ọdun 50 si 60 ati laanu, ko si arowoto fun rẹ. Awọn itọju ti o wa ni bayi ko nigbagbogbo ṣiṣẹ daradara.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.

Lichen amyloidosis jẹ ipo awọ yun ti o pẹ. O mọ fun awọn iṣupọ ti awọn bumps ti o nipọn ni akọkọ ti a rii ni ẹhin, awọn didan, itan, ati awọn apa. Nigbati a ba ṣe ayẹwo labẹ maikirosikopu, Lichen amyloidosis ṣe afihan ikojọpọ amyloid ni ipele oke ti awọ ara pẹlu nipọn ati imugboroja ti awọ ara ita. Bi o ti jẹ pe idi gangan ti Lichen amyloidosis ko ni oye ni kikun sibẹsibẹ, awọn iwadii iṣaaju ti sopọ mọ awọn okunfa bii fifipa tabi ija lori awọ ara, iku sẹẹli, awọn akoran ọlọjẹ, laarin awọn miiran. Lichen amyloidosis dabi pe o ni asopọ pẹlu ọpọlọpọ awọn ipo awọ ara miiran (atopic dermatitis, lichen planus, mycosis fungoides) .
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.