Alaye siwaju sii ― Yoruba

Arábìnrin kan, ọmọ ọdún 26, wá sí ilé‑ìwòsàn wa nípa ìròyìn pé ó ń ní rirun yún lórí ẹsẹ̀ rẹ̀ tí ó ti ń ní fún ọdún mẹ́wàá. Pẹ̀lú lílo corticosteroid cream àti tazarotene cream, àìlera kò rọrùn. Kò ní ìtàn ìdílé tó yẹ. Nígbà tí a ṣe àyẹ̀wò rẹ̀, a rí àwọ̀ tí ó gbé sórí, tí ó gùn ní iwájú ẹsẹ̀ rẹ̀, tí ó bá àìsàn kan tí a ń pè ní lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.

Lichen Amyloidosis jẹ ipo awọ ti o ṣọwọn ti o ni asopọ pẹlu ikojọpọ amyloid ti ko mọ idi rẹ. Nigbagbogbo o farahan gẹgẹbi awọn iṣupọ ti n dide, awọn abulẹ ti ko ni awọ lori awọn ita awọ ara. Lichen Amyloidosis maa n farahan ninu awọn eniyan ti o wa laarin ọdun 50 ati 60, ati laanu, ko si itọju to daju fun rẹ. Awọn itọju to wa lọwọlọwọ ko nigbagbogbo ṣiṣẹ daradara.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.

Lichen amyloidosis jẹ ipo awọ ti o pẹ̀. Ó mọ̀ fún àkójọpọ̀ àwọn àkúnya tó ń dínà ní àgbègbè ẹ̀yìn, àyà, ìtàn, àti àwọn apá míì. Nígbà tí a ṣe àyẹ̀wò rẹ̀ ní àbáwọ̀n microscope, Lichen amyloidosis ń fi hàn ìkójọpọ̀ amyloid ní ipele òkè ti awọ ara pẹ̀lú àkúnya àti ìmúgbòòrò ti awọ ara òde. Bí ó tilẹ̀ jẹ́ pé àǹfààní gidi ti Lichen amyloidosis kò tíì dájú ní kikún, àwọn ìwádìí ṣáájú ti ṣàfihàn pé ó lè ní í ṣe pẹ̀lú àwọn àǹfààní bíi fífi àìlera tàbí ija lórí awọ ara, ikú sẹẹ́lì, àrùn ọlọ́jẹ, àti bẹ́ẹ̀ bẹ́ẹ̀ lọ. Lichen amyloidosis dàbí pé ó ní ìbáṣepọ̀ pẹ̀lú ọ̀pọ̀lọpọ̀ àìlera awọ ara míì (atopic dermatitis, lichen planus, mycosis fungoides).
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.