Angiofibroma
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ReferencesCutaneous angiofibromas le hàn lórí oríṣìíríṣìí àwọ̀n ara. Lórí ojú, wọ́n máa ń mọ̀ bí papules fibrous tàbí adenoma sebaceum; lórí kòfẹ, a ń pè wọ́n ní pearly penile papules; lábẹ́ eekanna, a ń pè wọ́n ní periungual angiofibromas tàbí àwọn èèmọ Koenen; àti ní ẹnu, a tọ́ka sí wọ́n gẹ́gẹ́ bí fibromas oral. Angiofibromas ojú jẹ́ àfihàn pàtàkì ti tuberous sclerosis (TS), àìlera tí a jogún tó kan awọ ara, kidinrin, ọkan, ọpọlọ, àti ẹdọ. Nígbà ìgbà ọmọde tàbí àgbà, wọ́n sábà máa ń dàgbà lórí ojú nínú àwọn ẹni tí ó ní TS. Ní fífi mẹ́ta tàbí ju bẹ́ẹ̀ lọ ti angiofibromas ojú, tàbí méjì tàbí ju bẹ́ẹ̀ lọ ti angiofibromas àgbègbè, jẹ́ àpẹẹrẹ pàtàkì fún ìdánimọ̀ TS. Ní àfikún, ọ̀pọ̀ angiofibromas ojú lè hàn ní àwọn àìlera bíi multiple endocrine neoplasia type 1 (MEN-1) àti Birt-Hogg-Dubé syndrome. Pearly penile papules ń hàn lẹ́bàá àlà-awọ́ ọkàn àti sulcus ti kòfẹ. Wọ́n jẹ́ aláìlera, kò ní irora, a sì máa rí i ní ọkùnrin aláìkọ́là.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
1) Ojú – Fibrous papule
2) Kòfẹ – Pearly penile papule
3) Labẹ eekanna ika tàbí ika ẹsẹ – Periungual angiofibroma