Keloid
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Ninu awọn abajade 2022 Stiftung Warentest lati Jẹmánì, itẹlọrun alabara pẹlu ModelDerm jẹ kekere diẹ ju pẹlu awọn ijumọsọrọ telemedicine isanwo.
Ninu awọn abajade 2022 Stiftung Warentest lati Jẹmánì, itẹlọrun alabara pẹlu ModelDerm jẹ kekere diẹ ju pẹlu awọn ijumọsọrọ telemedicine isanwo.
Keloid lẹhin iṣẹ abẹ lori ọwọ ti a ti ṣe itọju pẹlu abẹrẹ intralesional triamcinolone. Agbegbe erythema ti o ṣubu wa ni apa osi ti agbegbe itọju.
Linear Keloids. Nigbati wọn ba waye lori iwaju oke ti torso, wọn maa n farahan bi ila kan.
Keloid auricular lẹhin
Keloids lori awọn atẹlẹsẹ le jẹ korọrun fun ririn. A maa n ṣe abẹrẹ sitẹriọdu intralesional ni igba pupọ.
A maa n ri Keloids nigbagbogbo lori awọn apa oke.
Ifihan àkótán ti àwọn keloids àyà.
relevance score : -100.0%
ReferencesKeloids dagba nitori iṣegun ti ko dara lẹhin ipalara awọ-ara tabi gbuuru. Jiini ati awọn ifosiwewe ayika ṣe alabapin si idagbasoke wọn, pẹlu awọn oṣuwọn ti o ga julọ laarin awọn eniyan dudu ti Afirika, Esia, ati awọn ara Hispaniki. Keloids waye nigbati awọn fibroblasts di alaapọn, ti n ṣe iṣelọpọ kolaginni pupọ ati awọn ifosiwewe idagbasoke. Eyi nyorisi idasile nla ti awọn edidi collagen ajeji ti a mọ si keloidal collagen, pẹlu ilosoke ninu nọmba awọn fibroblasts. Ni ile-iwosan, keloids hàn gẹ́gẹ́ bí àwọ̀n nódùlù tí ó ní àfarawà (rubbery) ní àgbègbè tí ó ti fara pàtàkì. Kò dàbí àwọn àlẹ̀bù àtọkànwá, keloids ń gbọ́nà ju àgbègbè ibajẹ́ àtẹ̀lẹ̀wọ̀ lọ. Àwọn aláìsàn lè ní iriri irora, nyún, tàbí sisun. Ọ̀pọ̀lọpọ̀ ìtọ́jú wà, pẹ̀lú abẹrẹ steroid, cryotherapy, iṣẹ́ abẹ, radiotherapy, àti itọju laser.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Iwadi lọwọlọwọ ni imọran pé gel silikoni tàbí dì pẹ̀lú àwọn abẹrẹ corticosteroid jẹ́ itọju àkọ́kọ́ tí a fẹ́ fún àwọn keloids. Àwọn itọju àfikún bíi intralesional 5-fluorouracil (5-FU), bleomycin, tàbí verapamil tún lè ṣe àfihàn, bí ó tilẹ̀ jẹ́ pé imunadoko wọn yàtọ̀. Itọju laser, nígbà tí a bá darapọ̀ rẹ̀ pẹ̀lú àwọn abẹrẹ corticosteroid tàbí àwọn steroid agbègbè labẹ occlusion, lè mu ilaluja àwọn òògùn pọ̀ síi. Fún àwọn keloids recalcitrant, yiyọ iṣẹ‑abẹ tí ó tẹ̀lé pẹ̀lú itọju laser lẹ́sẹ̀kẹsẹ ti fìhàn pé ó munadoko. Ní ikẹhin, lílo silikoni dì àti itọju laser tí a ti fìhàn láti dín àǹfààní ìtúnṣe keloid kù.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
Lọwọlọwọ, ko si itọju kan ti o ba gbogbo eniyan mu ti o ṣe iṣeduro oṣuwọn atunṣe kekere nigbagbogbo fun keloids. Sibẹsibẹ, awọn aṣayan tuntun, bii lilo laser lẹgbẹẹ sitẹriọdu tabi apapọ 5-fluorouracil pẹlu sitẹriọdu, ti n fihan ileri. Iwadi ọjọ iwaju le dojukọ bi awọn itọju tuntun, gẹgẹbi jijẹ ọra ara ẹni tabi awọn itọju ti o da lori sẹẹli, ṣe le ṣiṣẹ fun iṣakoso keloids.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
Awọn aleebu jẹ apakan ti o wọpọ ninu ilana imularada lẹhin awọn ipalara awọ ara. Gẹgẹ bí ó ti yẹ, awọn aleebu yẹ kí ó jẹ́ alapin, tinrin, kí ó sì bá awọ ara mu. Ọ̀pọ̀lọpọ̀ àwọn okunfa lè fa ìwòsàn ọ̀gbẹ́ tí kò dára, bíi ikolu, sisan ẹ̀jẹ̀ tí ó dínkù, ischemia, àti ibalokanjẹ. Awọn aleebu tí ó ní ìpò tó gùn, dudu ju awọ ara agbegbe lọ, tàbí tí ó dínkù gan-an lè fa àwọn ìṣòro pàtàkì nípa iṣẹ́ ara àti ilera ẹ̀dá.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Àwọn àlẹ̀bù Keloid máa ń hàn ní àkúnya àwọn ènìyàn Afríkà, Asia, tàbí àwọn tí ó ní ìdílé Hispaniki. Ẹni tó wà láàárín ọdún 10 sí 30 ni ìfarahan tó ga jùlọ láti ní keloid ju àwọn agbalagba lọ.
Bí ó tilẹ̀ jẹ́ pé wọ́n sábà máa ń hàn ní àgbègbè tí ìfarapa kan wáyé, keloid tún lè dide láì ní ìfarapa kankan. Ó lè hàn ní àgbègbè tí ó ní lilu, tàbí láti ohun tó rọrùn bí pimple tàbí ibere. Ó tún lè wáyé gẹ́gẹ́ bí abajade irorẹ tó lagbara, ọ̀gbẹ́ adiẹ, ikọlu ní àgbègbè ọ̀gbẹ́, àìlera tó wáyé sí agbègbè kan, àìdá àdánù awọ̀ ara tó pọ̀jù nígbà tí ọ̀gbẹ́ bá ń pa, tàbí ohun tí kò yẹ kí ó wà nínú ọ̀gbẹ́.
Àwọn àlẹ̀bù Keloid lè dide lẹ́yìn iṣẹ́ abẹ. Wọ́n wọ́pọ̀ jùlọ ní àwọn àgbègbè bí aarin àyà (látinú sternotomy), ẹ̀hìn àti àwọn ejika (tí ó sábà máa ń wáyé láti irorẹ), àti àwọn lobes eti (látinú lilu eti). Wọ́n tún lè hàn lórí àwọn lilu ara. Àwọn àgbègbè tó wọ́pọ̀ jùlọ ni àwọn eti, àwọn àpá, agbègbè pelvic, àti lórí egungun kola.
Àwọn ìtọ́jú tó wà fún keloid ni: titẹ, silikoni gel sheeting, intra‑lesional triamcinolone acetonide, cryosurgery, radiation, laser therapy, interferon, 5‑FU, àti excision abẹ.
○ Itọju
Àwọn àlẹ̀bù hypertrophic lè yọ̀ọ́dá pẹ̀lú 5 sí 10 ìtẹ̀jáde intralesional triamcinolone acetonide ní àárín oṣù kan.
#Triamcinolone intralesional injection
Itọju lesa lè dènà erythema tó ní í ṣe pẹ̀lú ọ̀gbẹ́, ṣùgbọ́n àwọn abẹrẹ triamcinolone tún lè dín erythema náà kù nípa dídán àlẹ̀bù náà.
#Dye laser (e.g. V‑beam)