Lymphangioma
Lymphangioma jẹ awọn aiṣedeede ti eto iṣan-ara ti o jẹ ifihan nipasẹ awọn egbo ti o jẹ awọn cysts ti o ni odi tinrin. Awọn aiṣedeede wọnyi le waye ni ọjọ-ori eyikeyi ati pe o le kan eyikeyi apakan ti ara, ṣugbọn 90% waye ninu awọn ọmọde ti o kere ju ọdun 2 ti ọjọ-ori ati pẹlu ori ati ọrun. Awọn lymphangiomas ti a gba le ja lati ibalokanjẹ, igbona, tabi idinamọ lymphatic. Niwọn igba ti wọn ko ni aye lati di alaburuku, awọn lymphangiomas nigbagbogbo ni itọju fun awọn idi ohun ikunra nikan.
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References
Lymphangioma tun ni a mọ bi aiṣedeede lymphatic (LM) . O jẹ iṣọn-ẹjẹ iṣan ti o wa lati ibimọ. O jẹ ifihan nipasẹ idagbasoke ajeji ti àsopọ lymphatic ṣaaju ati lẹhin ibimọ. Lymphangioma kan nipa 1 ni 2000 si 4000 eniyan, laisi iyatọ pataki laarin awọn akọ tabi abo. Ọpọlọpọ awọn ọran (80-90%) ni a ṣe ayẹwo ṣaaju ọjọ-ori meji. Awọn aami aisan yatọ si pupọ, lati wiwu agbegbe si awọn aiṣedeede lọpọlọpọ ninu awọn ikanni lymphatic, nigbami o yori si wiwu lile ti a mọ si elephantiasis. Fun apẹẹrẹ, lymphangioma ni ọrun ati oju le fa wiwu oju, ati ni awọn iṣẹlẹ ti o buruju, ibajẹ. Nigba ti o ba kan ahọn, o le ja si ẹrẹkẹ ati awọn eyin ti ko tọ. Ni ẹnu ati ọrun, o le fa awọn iṣoro mimi ati awọn pajawiri ti o lewu. Ni awọn oju, o le fa ipadanu iran, gbigbe oju ti o ni opin, awọn ipenpeju sisọ, ati awọn oju didan. Ilowosi ọwọ le fa wiwu ati idagbasoke ajeji ti awọn ara ati awọn egungun. Egbo yii maa n dagba laiyara, ṣugbọn awọn akoran, awọn iyipada homonu, tabi ipalara le fa idagbasoke ni kiakia, ti o nfa awọn ewu ti o lewu ti o nilo itọju ni kiakia.
Lymphangioma (lymphatic malformation, LM), a congenital vascular disease, is a low-flow vascular abnormality in lymphatic diseases that is characterized by excessive growth of lymphatic tissue during prenatal and postpartum development. The incidence rate of LM is ~1:2000–4000, with no variation between genders and races. Most patients (80–90%) are diagnosed before the age of two. The clinical manifestations of lymphangioma are quite different among patients, varying from local swelling leading to superficial mass to a large area of diffuse infiltrating lymphatic channel abnormalities resulting in elephantiasis. Cervicofacial LM can cause facial elephantiasis, and in some severe cases, it can lead to serious disfigurement of the face. Tongue LM can lead to mandibular overgrowth and occlusal asymmetry, and oral and cervical LM can cause obstructive acute respiratory distress and life-threatening situations. Orbital LM may lead to decreased vision, decreased extraocular muscle movement, ptosis and exophthalmos. LM of the extremities can trigger swelling or gigantism, accompanied by overgrowth of soft tissue and bones. LM usually grows slowly and steadily, but under certain conditions, such as infection, hormonal changes or trauma, it can grow explosively and become a life-threatening disease requiring immediate treatment.
Lymphangioma (lymphatic malformation, LM), a congenital vascular disease, is a low-flow vascular abnormality in lymphatic diseases that is characterized by excessive growth of lymphatic tissue during prenatal and postpartum development. The incidence rate of LM is ~1:2000–4000, with no variation between genders and races. Most patients (80–90%) are diagnosed before the age of two. The clinical manifestations of lymphangioma are quite different among patients, varying from local swelling leading to superficial mass to a large area of diffuse infiltrating lymphatic channel abnormalities resulting in elephantiasis. Cervicofacial LM can cause facial elephantiasis, and in some severe cases, it can lead to serious disfigurement of the face. Tongue LM can lead to mandibular overgrowth and occlusal asymmetry, and oral and cervical LM can cause obstructive acute respiratory distress and life-threatening situations. Orbital LM may lead to decreased vision, decreased extraocular muscle movement, ptosis and exophthalmos. LM of the extremities can trigger swelling or gigantism, accompanied by overgrowth of soft tissue and bones. LM usually grows slowly and steadily, but under certain conditions, such as infection, hormonal changes or trauma, it can grow explosively and become a life-threatening disease requiring immediate treatment.
Ninu iwadi ifẹhinti yii, a ṣe ayẹwo awọn ọmọde 24 ti wọn ni lymphangioma ti wọn si ṣe itọju pẹlu awọn abẹrẹ ti ojutu bleomycin lati January 1999 si Kejìlá 2004. Pupọ ninu awọn egbo (63%) ti lọ patapata, 21% ni idahun to dara, ati 16% ko dahun daradara. Awọn alaisan meji ni èèmọ naa pada nigbamii, ati pe awọn meji miiran ni abscesses nibiti wọn ti gba awọn abẹrẹ naa. Ni Oriire, a ko rii awọn iṣoro nla miiran tabi awọn ipa ẹgbẹ.
This is a retrospective study of 24 children diagnosed with lymphangioma and treated with intralesional injection of bleomycin aqueous solution from January 1999 to December 2004. Complete resolution was seen in 63% (15/24) of lesions, 21% (5/24) had good response and 16% (4/24) had poor response. The tumour recurred in 2 patients. Two other patients had abscess formation at the site of injection. No other serious complications or side effects were observed.
This is a retrospective study of 24 children diagnosed with lymphangioma and treated with intralesional injection of bleomycin aqueous solution from January 1999 to December 2004. Complete resolution was seen in 63% (15/24) of lesions, 21% (5/24) had good response and 16% (4/24) had poor response. The tumour recurred in 2 patients. Two other patients had abscess formation at the site of injection. No other serious complications or side effects were observed.
Awọn oriṣi akọkọ ti lymphangioma jẹ bi atẹle - lymphangioma circumscriptum, cavernous lymphangioma, cystic hygroma, lymphangioendothelioma. Iwọnyi jẹ ni ayika 26% ti awọn èèmọ iṣọn-ẹjẹ alaiṣe ni awọn ọmọde ṣugbọn ko wọpọ ni awọn agbalagba. Lymphangioma circumscriptum , iru loorekoore julọ, ṣe afihan awọn iṣan lymphatic ti n jade nipasẹ awọ ara, ti o n ṣe awọn vesicles ti o ni ito ko o ti o jọra si spawn ọpọlọ, pẹlu wiwu ti ara. Nigbagbogbo o han lori awọn agbegbe pẹlu nẹtiwọọki lymphatic ọlọrọ bi awọn ọwọ, ẹhin mọto, ati awọn apa. Arabinrin kan ti o jẹ ẹni ọdun 71 wa si ile-iwosan wa pẹlu wiwu ẹsẹ ti o tẹsiwaju, awọn gbigbo Pink lori awọn ẹya ara rẹ, nyún, ati omi ti o n jo. A yọ gbogbo awọn bumps kuro ni iṣẹ-abẹ pẹlu ilana ti a npe ni labiectomy pataki meji, ti o duro ni ipele Colles' fascia, lakoko ti o tọju idoti ati mẹrin.
The predominant types of lymphangioma are lymphangioma circumscriptum (LC), cavernous lymphangioma, cystic hygroma, and lymphangioendothelioma. These entities account for approximately 26% of benign vascular tumors in children but are rarer in adults. LC is the most common form of cutaneous lymphangioma and is characterized by superficial lymphatic ducts protruding through the epidermis. This condition results in clusters of clear fluid-filled vesicles resembling frog spawn and associated tissue edema. It is usually found on the proximal extremity, trunk, and axilla, which has an abundant lymphatic system. A 71-year-old female presented to our outpatient clinic with persistent edema of both lower limbs, clusters of pink labial papules, pruritus, and watery lymph oozing. We removed all the papules by performing bilateral major labiectomy down to the level of Colles' fascia, sparing the clitoris and fourchette.
The predominant types of lymphangioma are lymphangioma circumscriptum (LC), cavernous lymphangioma, cystic hygroma, and lymphangioendothelioma. These entities account for approximately 26% of benign vascular tumors in children but are rarer in adults. LC is the most common form of cutaneous lymphangioma and is characterized by superficial lymphatic ducts protruding through the epidermis. This condition results in clusters of clear fluid-filled vesicles resembling frog spawn and associated tissue edema. It is usually found on the proximal extremity, trunk, and axilla, which has an abundant lymphatic system. A 71-year-old female presented to our outpatient clinic with persistent edema of both lower limbs, clusters of pink labial papules, pruritus, and watery lymph oozing. We removed all the papules by performing bilateral major labiectomy down to the level of Colles' fascia, sparing the clitoris and fourchette.
