Melasmahttps://en.wikipedia.org/wiki/Melasma
Melasma jẹ awọ-ara tabi awọ dudu ti oju. Melasma ni a ro pe o ṣẹlẹ nipasẹ ifihan oorun, asọtẹlẹ jiini, awọn iyipada homonu, ati irrita awọ ara. Botilẹjẹpe o le kan ẹnikẹni, o wọpọ julọ ni awọn obinrin, paapaa awọn obinrin ti o loyun ati awọn ti o mu awọn itọju oyun tabi awọn oogun itọju aropo homonu.

Melasma ko le ṣe ipinnu pẹlu itọju laser fun akoko kan, nitori pe o jẹ arun ninu eyiti o jẹ iṣelọpọ awọ nigbagbogbo. Tranxenemic acid ṣe iranlọwọ lati ni ilọsiwaju lati dinku pigmentation.

Itọju
Ni diẹ ninu awọn orilẹ-ede (fun apẹẹrẹ Japan, Korea), tranexamic acid ẹnu wa lori counter ati pe o munadoko. Ipara melasma pẹlu tranexamic acid ati azelaic acid le jẹ iranlọwọ ni apakan.
Hydroquinone le ṣee lo ni oke fun itọju hyperpigmentation, ṣugbọn FDA dawọ awọn ọja OTC ti o ni hydroquinone ninu bi ti 2020.
#Tranexamic acid [TRANSINO]

#Laser toning technique (low fluence QS1064 laser)
#Triluma
☆ Ninu awọn abajade 2022 Stiftung Warentest lati Jẹmánì, itẹlọrun alabara pẹlu ModelDerm jẹ kekere diẹ ju pẹlu awọn ijumọsọrọ telemedicine isanwo.
  • O jẹ ipo ti o wọpọ ti a ṣe akiyesi ni awọn obinrin Asia ni ibẹrẹ 40s wọn. Egbo yiyi ni fọto sunmo lentigo kuku ju melasma lọ.
    References Efficacy and Safety of Tranexamic Acid in Melasma: A Meta-analysis and Systematic Review 28374042
    Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
     The Low-Fluence Q-Switched Nd:YAG Laser Treatment for Melasma: A Systematic Review 35888655 
    NIH
    Laipẹ, laser low-fluence Q-switched Nd:YAG (LFQSNY) ti di olokiki fun atọju melasma, paapaa ni Asia. Akopọ awọn ijinlẹ oniruuru jẹ nija, ṣugbọn LFQSNY dabi iwulo gbogbogbo ati ailewu fun melasma ni akawe si awọn itọju ti aṣa. Bibẹẹkọ, diẹ ninu awọn ọran ti hypopigmentation mottled ni a ti royin bi ipa ẹgbẹ ti LFQSNY, o ṣee ṣe nitori agbara laser giga. Lilo ibinu ti LFQSNY tun le ja si hyperpigmentation lati iredodo, paapaa ni awọn ohun orin awọ dudu.
    Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
     Pigmentation Disorders: Diagnosis and Management 29431372
    Awọn iṣoro pigmentation nigbagbogbo ni a rii ni itọju akọkọ. Awọn oriṣi wọpọ ti awọn rudurudu hyperpigmentation pẹlu post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
    Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.