Onychomysosishttps://en.wikipedia.org/wiki/Onychomycosis
Onychomycosis jẹ ikolu olu ti àlàfo. Awọn aami aisan le pẹlu iyipada awọ eekanna funfun tabi ofeefee, didan ti àlàfo, àti iyapa àlàfo kuro ninu ibusun àlàfo. Awọn eekanna ika ẹsẹ tàbí eekanna ika le ní ipa, ṣùgbọ́n ó wọ́pọ̀ jùlọ fún eekanna ika ẹsẹ. Awọn ilolu le pẹlu cellulitis ti ẹsẹ isalẹ. Nọmba awọn oriṣiriṣi fungus le fa onychomycosis, pẹlu dermatophytes. Awọn okunfa ewu pẹlu ẹsẹ elere‑ije, awọn arun eekanna miiran, ifihan si ẹni tí ó ní ipo náà, arun iṣan agbeegbe, àti iṣẹ ajẹsara tí kò dára. Oogun antifungal terbinafine tí a mu ní ẹnu dabi ẹni pé ó munadoko jùlọ, ṣùgbọ́n ó lè ní ipa ẹgbẹ lórí ẹdọ. Onychomycosis waye ninu 10 % ti olùgbé àgbàlagbà, pẹ̀lú àwọn àgbàlagbà tí ó ní ipa nigbagbogbo. Awọn ọkùnrin ní ipa diẹ̀ síi ju àwọn obìnrin lọ. Onychomycosis dúró fún bíi idájọ́ arun eekanna. Èyí túmọ̀ sí pé ìdíbàjẹ́ ti àwọn eekanna ika ẹsẹ lè tún wá láti àwọn okunfa míì ju onychomycosis lọ. ○ Itọju - Oògùn OTC O nira láti tọju onychomycosis pẹ̀lú àwọn oogun tó wà ní agbègbè nitori pé ó ṣòro fún àwọn oogun láti wọ̀ àwọn eekanna ika ẹsẹ tó ní ìpò tó gùn. #Ketoconazole
#Clotrimazole
#Miconazole
#Terbinafine
#Butenafine [Lotrimin]
#Tolnaftate

Itọju Itọju igba pipẹ ní a nílò nigbagbogbo títí tí eekanna ika ẹsẹ tó ní arun yóò fi yọ́ kúrò patapata. #Terbinafine (oral)
#Itraconazole
#Efinaconazole lacquer [Jublia]
#Ciclopirox lacquer
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  • Ẹ̀kànná ika ẹsẹ kan tí ó kan Onychomycosis
  • Ẹni tí ó ní àrùn eékànná fún ọ̀sẹ̀ mẹ́wàá, ń lo oogun ẹnu terbinafine. Ṣe àkíyèsí àwọn àkúnya ilera tó lè hàn lẹ́yìn ìtẹ̀síwájú àrùn eékànná.
  • Ọran ti arun olu lori ika ẹsẹ ńlá.
References Onychomycosis: Current trends in diagnosis and treatment 24364524
Awọn antifungal eto jẹ itọju ti o munadoko julọ. Itupalẹ meta fihan awọn oṣuwọn imularada mycotic gẹgẹ bi atẹle: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole = 48% . Yiyọkuro eekanna concomitant siwaju sii mu awọn oṣuwọn imularada pọ si. Itọju ailera pẹlu ciclopirox ko munadoko; o ni oṣuwọn ikuna ti o ju 60% lọ.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
 Onychomycosis 28722883 
NIH
Onychomycosis jẹ akoran olu ti o kan eekanna. Nigbati o ba ṣẹlẹ nipasẹ awọn dermatophytes, a pe e ni tinea unguium. Onychomycosis pẹlu awọn akoran ti a fa nipasẹ dermatophytes, iwukara, ati m. Iṣoro eekanna ti ko jẹ abajade akoran olu ni a mọ si nail dystrophy. Botilẹjẹpe o le kan eekanna ika ati eekanna ẹsẹ, onychomycosis toenail jẹ wọpọ julọ. Nkan yii yoo jiroro lori ọpọlọpọ awọn ẹya ti onychomycosis ika ẹsẹ, gẹgẹ bi ipa rẹ, awọn iru itọju, awọn ipele, iwadii aisan, ati itọju. Bó tilẹ̀ jẹ́ pé kò ní í dákẹ́ ààyè, onychomycosis lè yọrí sí àwọn àìlera tó ṣe pàtàkì bí cellulitis, sepsis, ikolu egungun, ibajẹ ara, àti isonu eekanna.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
 Terbinafine 31424802 
NIH
Terbinafine jẹ́ oogun kan tí ó ń koju àwọn àkóràn olú nípa didi squalene epoxidase. Ó munadoko lòdì sí ọ̀pọ̀ irú àìlera ara, ó sì ti fọwọ́sí fún ìtọ́jú fungus eekanna nígbà tí a bá mu un ní ẹnu. Bí ó tilẹ̀ jẹ́ pé ọ̀pọ̀ àkúnya bíi efori àti àwọn ìṣòro inú jẹ́ kékeré, wọ́n sì ń bọ̀ lọ́wọ́ ara wọn, àyípadà nínú itọ́wọ́ (dysgeusia) lè yàtọ̀ láti ìdíwọ̀n díẹ̀ sí àìdá, nígbà míì tí ó lè yọrí sí pípadà àìlera. Àwọn àyípadà itọ́wọ́ tó wúlò jẹ́ tójé, ṣùgbọ́n wọ́n ti wà ní ìrọ̀rùn.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
 Onychomycosis: An Updated Review 31738146 
NIH
Onychomycosis jẹ akoran ti o ní ipa lori eekanna. Ní ayíká 90 % ti àwọn akóran eekanna ika ẹsẹ àti 75 % ti àwọn akóran eekanna ika ni a fà nípasẹ̀ elu (Trichophyton mentagrophytes, Trichophyton rubrum). Àwọn ààmì àìsàn ní í ṣe pẹ̀lú iyípadà eekanna, ìpò tó nipọn, ipinya láti ibùsùn àlàfo, àti ìdàgbàsókè tó pọ̀. Itọju máa ń jẹ́ pẹ̀lú àwọn oogun ẹnu bíi terbinafine tàbí itraconazole, nígbà tí àwọn itọju àgbègbè jẹ́ aṣàyàn fún àwọn ọ̀ràn kékeré tàbí tí kò ní ìwọ̀n tó gíga.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.