Alaye siwaju sii ― Yoruba

Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.

Panniculitis ṣe akojọpọ oriṣiriṣi ti awọn arun iredodo ti o kan si ara adipose subcutaneous. Awọn ailera wọnyi ṣọwọn ninu awọn ọmọde. Panniculitis le jẹ ilana akọkọ ni rudurudu eto tabi ilana keji ti o jẹ abajade lati ikolu, ibalokanjẹ tabi ifihan si oogun. Pupọ julọ ti panniculitis ni igbejade ile-iwosan kanna (laibikita ti aetiology) , pẹlu tutu, awọn nodules subcutaneous erythematous.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.

Panniculitis, igbona ti ọra subcutaneous, nigbagbogbo ṣafihan pẹlu awọn nodules iredodo. Erythema nodosum (EN) ni ile‑iwosan ti o wọpọ julọ ti panniculitis. Lakoko ti to 55 % ti EN jẹ idiopathic, awọn okunfa ti o wọpọ julọ pẹlu awọn akoran, awọn oogun, awọn aarun eto bii sarcoidosis ati arun ifun iredodo, oyun, àti aiṣedeede. EN maa n ṣafihan ní àwọn ọdọ àti ní ọdún 20, ó sì ń hàn jùlọ nínú àwọn obìnrin. Nigbagbogbo ó ṣáájú ilana tí kò ní àpẹẹrẹ fún ọ̀sẹ̀ kan sí mẹ́ta, èyí tí ó lè ní íbà, àìlera, àti àwọn ààmì àìsàn ti ikolu ti atẹ́gùn òkè. Àwọn egbo awọ‑ara lẹ́yìn náà tẹ̀lé, nígbà míì ní agbègbè extensor ti àwọn ẹsẹ̀. Àwọn egbo náà jẹ́ irora yíká tàbí ofali, díẹ̀ dídè, àwọn nodules pupa tí kò ní ọ̀gbẹ́. A kò mọ̀ pathogenesis gangan ti EN, bí ó tilẹ̀ jẹ́ pé a ro pé ó jẹ́ abajade ifisilẹ àwọn ẹ̀ka ajẹsara nínú àwọn ibi isere ti septae ní ọra subcutaneous, tí ń fa panniculitis neutrophilic. Pàápàá jùlọ, láìsí ìtòjú àìlera kan pàtó fún ipo okunfa, EN máa ń yanju láìsí ìtòjú ní ọ̀pọ̀lọpọ̀ ọ̀ràn.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.