Syphilis
https://en.wikipedia.org/wiki/Syphilis
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Secondary syphilis
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References
Secondary syphilis in cali, Colombia: new concepts in disease pathogenesis 20502522 NIH
Syphilis jẹ arun ti ibalopọ takọtabo ti o fa nipasẹ kokoro arun Treponema pallidum. Ninu iwadi yii, a fojusi awọn alaisan 57 ti ọjọ ori 18-68 pẹlu syphilis keji.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Syphilis 30521201 NIH
Syphilis jẹ akoran kokoro-arun ti o fa nipasẹ Treponema pallidum. O le fara wé orisirisi arun, jijere o ni apeso great imitator. Syphilis tun kan awọn miliọnu ni agbaye ṣugbọn a le ṣe itọju daradara pẹlu penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis 29022569 NIH
Treponema pallidum fa syphilis nipasẹ ibalopọ ibalopo tabi lati ọdọ iya si ọmọ lakoko oyun. Paapaa botilẹjẹpe awọn idanwo ti o rọrun wa lati ṣe iwadii aisan rẹ ati itọju pẹlu ibọn penicillin kan ti o ṣiṣẹ pipẹ ṣiṣẹ daradara, syphilis ti di iṣoro nla lẹẹkansii ni kariaye. Eyi jẹ otitọ paapaa laarin awọn ọkunrin ti o ni ibalopọ pẹlu awọn ọkunrin (MSM) ni awọn orilẹ-ede ti o ni owo-ori giga ati aarin. Lakoko ti diẹ ninu awọn orilẹ-ede ti owo-wiwọle kekere ti pade awọn ibi-afẹde WHO lati da syphilis ti n kọja lati ọdọ iya si ọmọ, idaamu idaamu wa ni syphilis laarin MSM ti o ni kokoro-arun HIV.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Congenital Syphilis 30725772 NIH
(1) Ẹ̀dọ̀ Tó Gbé: Èyí sábà máa ń rí, ó sì lè ṣẹlẹ̀ lẹ́gbẹ̀ẹ́ ẹ̀dọ̀ tó fẹ̀. Ṣiṣayẹwo biopsy ẹdọ labẹ microscopy aaye dudu le ṣafihan wiwa spirochete naa. Awọn idanwo iṣẹ ẹdọ le fihan awọn aiṣedeede. (2) Yellowing of the Skin (Jaundice) : Boya ẹnikan han jaundice da lori bi ẹdọ ṣe kan. (3) Imu imu: Nigbagbogbo ọkan ninu awọn ami akọkọ, nigbagbogbo laarin ọsẹ akọkọ lẹhin ibimọ. (4) Awọn apa Lymph Swollen: Wiwu gbogbogbo ti awọn apa ọmu-ara, nigbagbogbo laisi irora, tun wọpọ. (5) Awọ-ara-ara: sisu kan maa n han ni ọsẹ kan si meji lẹhin imu imu. O le rii awọn aaye pupa tabi Pink kekere ni ẹhin, awọn ibadi, itan, ati awọn atẹlẹsẹ ẹsẹ. Sisu yii le ni ilọsiwaju si peeling ati erunrun.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Ayẹwo ati Itọju
VDRL ati RPR le ṣee lo lati jẹrisi ikolu laipe ati iboju fun syphilis. Idanwo FTA-ABS jẹ idanwo kan pato ati pe o le ṣee lo lati ṣayẹwo fun itan-akọọlẹ ikolu ti tẹlẹ. Penicillin ni a lo lati tọju syphilis.