Toxic epidermal necrosishttps://en.wikipedia.org/wiki/Toxic_epidermal_necrolysis
Toxic epidermal necrosis jẹ́ àìlera tó ń kópa púpọ̀ ní awọ ara. Àwọn ààmì àìlera ibẹrẹ ni ìbà àti ìrora. Lẹ́yìn ọ̀pọ̀ ọjọ́, awọ ara máa ń rọ̀, tí ó sì ń yọ̀ sílẹ̀ ní àgbègbè tó ní ìrora. Ó ṣe pàtàkì kí àwọn membran mucous, bíi ẹnu, tún wà ní àìlera. Àwọn ìṣòro tó lè yọ̀ sílẹ̀ ni gbígbẹ́, sepsis, pneumonia, àti ikúpọ̀ àwọn ara.

Ọ̀pọ̀ jùlọ, àìlera yìí ń bọ̀ láti ọ̀dọ̀ àwọn oogun bí lamotrigine, carbamazepine, allopurinol, sulfonamide aporo, àti nevirapine. Àwọn àǹfààní ewu míì ni HIV àti lupus erythematosus (systemic). Itọju máa ń wáyé ní ilé‑ìwòsàn, gẹ́gẹ́ bí ICU tàbí apá itọju aládánla.

○ Itọju
Èyí jẹ́ àìlera tó ṣe pàtàkì, nítorí náà tí ẹnu, ẹ̀dá, tàbí awọ ara rẹ bá di rọ̀, kí o wá dókítà rẹ ní kété tí ó ti ṣeé ṣe.
Àwọn oogun tó fa àìlera náà yẹ kí wọ́n dáwọ́ dúró (fun àpẹẹrẹ, àwọn egboogi, àwọn oogun egboogi‑iredodo tí kì í ṣe corticosteroid).

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  • Isonu awọ ara abuda ti Toxic epidermal necrosis
  • TENS – ọjọ́ 10
  • Necrolysis epidermalis toxica
  • Awọn roro ni ibẹrẹ ipele le yara dagba ki o kan gbogbo ara laarin awọn ọjọ diẹ.
References Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Review of Diagnosis and Management 34577817 
NIH
Stevens-Johnson Syndrome (SJS) ati Toxic Epidermal Necrolysis (TEN) jẹ awọn ipo toje nibiti awọ ara ti ni iriri ibajẹ nla ati sisọ silẹ. Nípa itọju, cyclosporine jẹ imunadoko pupọ fun SJS, nígbà tí àpapọ̀ immunoglobulin inu iṣọn‑ẹjẹ (IVIg) àti corticosteroids ń ṣiṣẹ́ dáadáa jùlọ fún àwọn ọ̀ràn SJS àti TEN.
Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin. Regarding treatment, cyclosporine is the most effective therapy for the treatment of SJS, and a combination of intravenous immunoglobulin (IVIg) and corticosteroids is most effective for SJS/TEN overlap and TEN.
 Toxic Epidermal Necrolysis: A Review of Past and Present Therapeutic Approaches 36469487
Toxic epidermal necrolysis (TEN) jẹ àìlera awọ ara tó ṣe pàtàkì tí ó ń ṣẹlẹ̀ nípasẹ̀ àwọn oogun kan àti ìbáṣepọ̀ pẹ̀lú eto àjẹsára, tí ó ń yọ̀kúrò àgbáyé ńlá ti epidermis, tó kàn ju 30 % ti ara. TEN ní oṣùwàn ìkú tó ju 20 % lọ, nígbà míì nítorí àrùn àkóràn àti ìṣòro mími. Ìdákẹ́jẹ́ẹ̀jẹ́ oogun tó ń fa ìfesi, pèsè ìtọ́jú àtìlẹ́yìn, àti lílo àwọn ìtọ́jú àfikún lè mú àbájáde dára síi. Àwọn ìwádìí tuntun ti fi hàn pé àwọn oogun bíi cyclosporine, tumor necrosis factor‑alpha inhibitors, àti àpapọ̀ immune globulin (ajẹsara globulin) pẹ̀lú corticosteroids lè rànlọ́wọ́, gẹ́gẹ́ bí ìdánwò àkóso àìlẹ́tò àti àtúpalẹ̀ àwọn ìwádìí púpọ̀.
Toxic epidermal necrolysis (TEN) is a serious skin reaction caused by certain medications and immune system activity, resulting in large-scale detachment of the outer skin layer (epidermis), affecting more than 30% of the body's surface. TEN has a mortality rate of over 20%, often due to infections and breathing difficulties. Stopping the medication causing the reaction, providing supportive care, and using additional treatments can improve the outcome. Recent studies have shown that drugs like cyclosporine, tumor necrosis factor alpha inhibitors, and a combination of intravenous immune globulin and corticosteroids can be helpful, based on randomized controlled trials and analyses of multiple studies.
 Toxic Epidermal Necrolysis and Steven–Johnson Syndrome: A Comprehensive Review 32520664 
NIH
Recent Advances: There is improved understanding of pain and morbidity with regard to the type and frequency of dressing changes. More modern dressings, such as nanocrystalline, are currently favored as they may be kept in situ for longer periods. The most recent evidence on systemic agents, such as corticosteroids and cyclosporine, and novel treatments, are also discussed.