Urticaria
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References
Acute and Chronic Urticaria: Evaluation and Treatment 28671445Urticaria, nigbagbogbo ti o ni ijuwe nipasẹ awọn whal yun ati nigba miiran wiwu ti awọn ipele awọ ara ti o jinlẹ, ni igbagbogbo ni iṣakoso nipasẹ yago fun awọn okunfa, ti o ba mọ. Itọju akọkọ jẹ pẹlu awọn antihistamines H1 iran-keji, eyiti o le ṣe atunṣe si awọn iwọn giga ti o ba nilo. Ni afikun, awọn oogun miiran bii awọn antihistamines H1 iran akọkọ, awọn antihistamines H2, awọn antagonists olugba leukotriene, awọn antihistamines ti o lagbara, ati awọn iṣẹ kukuru ti awọn corticosteroids le ṣee lo lẹgbẹẹ. Fun awọn ọran itẹramọṣẹ, itọkasi si awọn alamọja fun awọn itọju miiran bi omalizumab tabi cyclosporine ni a le gbero.
Urticaria, often characterized by itchy wheals and sometimes swelling of the deeper skin layers, is typically managed by avoiding triggers, if known. The primary treatment involves second-generation H1 antihistamines, which can be adjusted to higher doses if needed. Additionally, other medications like first-generation H1 antihistamines, H2 antihistamines, leukotriene receptor antagonists, potent antihistamines, and short courses of corticosteroids may be used alongside. For persistent cases, referral to specialists for alternative therapies like omalizumab or cyclosporine may be considered.
Urticaria and Angioedema: an Update on Classification and Pathogenesis 28748365
Chronic Urticaria 32310370 NIH
Second-generation H1-antihistamines (e.g., cetirizine, loratadine, fexofenadine), Omalizumab, Ciclosporin, and short courses only of systemic corticosteroids
Angioedema 30860724 NIH
Angioedema jẹ wiwu ti ko lọ kuro ni ọfin nigba titẹ, ti o waye ni awọn ipele labẹ awọ ara tabi awọn membran mucous. O maa n kan awọn agbegbe bii oju, ète, ọrun, ati awọn ẹsẹ, bakanna bi ẹnu, ọfun, ati ikun. O di ewu nigbati o ba ni ipa lori ọfun, ti o le fa ipo ti o lewu.
Angioedema is non-pitting edema that involves subcutaneous and/or submucosal layers of tissue that affects the face, lips, neck, and extremities, oral cavity, larynx, and/or gut. It becomes life-threatening when it involves the larynx.
Idena ni nipa yago fun ohunkohun ti o jẹ ti o fa ipo naa. Itọju jẹ deede pẹlu awọn antihistamines gẹgẹbi diphenhydramine ati ranitidine. Ni awọn iṣẹlẹ ti o lewu, awọn corticosteroids tabi awọn inhibitors leukotriene le tun ṣee lo. Mimu otutu otutu ayika jẹ tun wulo fun igba diẹ. Fun awọn iṣẹlẹ ti o ṣiṣe diẹ sii ju ọsẹ mẹfa awọn ajẹsara ajẹsara gẹgẹbi cyclosporin le ṣee lo.
O jẹ arun ti o wọpọ nitori nipa 20% eniyan ni o kan. Awọn ọran ti urticaria nla waye ni deede ni awọn ọkunrin ati awọn obinrin lakoko ti awọn ọran gigun ni o wọpọ julọ ni awọn obinrin. Awọn ọran ti urticaria nla jẹ wọpọ julọ laarin awọn ọmọde lakoko ti awọn ọran gigun ni o wọpọ julọ laarin awọn ti o jẹ arugbo. Ti o ba jẹ diẹ sii ju oṣu 2 lọ, o ma wa fun ọdun pupọ ati lẹhinna lọ kuro.
○ Itọju - Oògùn OTC
Urticaria nla maa n yanju laarin ọsẹ kan, ṣugbọn urticaria onibaje le ṣiṣe ni fun ọdun bi o tilẹ jẹ pe ọpọlọpọ ninu wọn lọ kuro ni aaye kan. Ninu ọran ti urticaria onibaje, a gba ọ niyanju lati mu antihistamine ni igbagbogbo ati duro fun u lati lọ funrararẹ.
Awọn antihitamines OTC. Cetirizine tabi levocetirizine munadoko diẹ sii ju fexofenadine ṣugbọn jẹ ki o sun.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
Fun urticaria onibaje, awọn antihistamines ti kii-drowsy gẹgẹbi fexofenadine ni o fẹ.
#Fexofenadine [Allegra]
#Diphenhydramine [Benadryl]
#Loratadine [Claritin]