ABNOM
relevance score : -100.0%
References众所周知，Q‑switched Nd:YAG 激光可以有效治疗太田痣及类似疾病。我们开展了一项研究，评估 high‑fluence 1064 nm Q‑switched Nd:YAG 激光对异常部位蒙古斑的疗效，并观察其是否会导致皮肤变亮。研究纳入 61 名患者，共计 70 处病变。其中一半病变接受激光治疗，另一半作为对照未接受治疗。我们使用体重秤和 Mexameter® 测定黑色素水平，以评估疗效。治疗组患者平均随访 14 个月，对照组平均随访 18 个月。研究结束时，治疗组在量表评分和黑色素水平上均显著优于对照组，显示出更好的疗效。high‑fluence Q‑switched Nd:YAG 激光未引起皮肤变亮，证实其对这些罕见蒙古斑的治疗既有效又安全。
The Q-switched Nd:YAG laser is known to effectively treat nevus of Ota and similar conditions. We conducted a study to see how well a high-fluence 1064 nm Q-switched Nd:YAG laser worked on Mongolian spots in unusual areas, without causing the skin to lighten. We studied 61 patients with these spots, examining a total of 70 lesions. Half of lesions were treated with the laser, while others were left untreated for comparison. We evaluated the results using a scale and a device called a Mexameter® to measure melanin levels. Patients were followed up for an average of 14 months in the treatment group and 18 months in the observation group. At the end of the study, we found significant differences in the scale scores and melanin levels between the treated and untreated groups, with the laser-treated group showing better outcomes. The high-fluence Q-switched Nd:YAG laser, without causing skin lightening, proved effective and safe for treating these unusual Mongolian spots.
The Q-switched Nd:YAG laser is known to effectively treat nevus of Ota and similar conditions. We conducted a study to see how well a high-fluence 1064 nm Q-switched Nd:YAG laser worked on Mongolian spots in unusual areas, without causing the skin to lighten. We studied 61 patients with these spots, examining a total of 70 lesions. Half of lesions were treated with the laser, while others were left untreated for comparison. We evaluated the results using a scale and a device called a Mexameter® to measure melanin levels. Patients were followed up for an average of 14 months in the treatment group and 18 months in the observation group. At the end of the study, we found significant differences in the scale scores and melanin levels between the treated and untreated groups, with the laser-treated group showing better outcomes. The high-fluence Q-switched Nd:YAG laser, without causing skin lightening, proved effective and safe for treating these unusual Mongolian spots.
本研究评估了特定激光治疗 ABNOM 的有效性和安全性，并探讨了影响疗效的因素。共纳入 110 名接受 2 至 9 次激光治疗的 ABNOM 患者。结果显示，治疗次数越多，疗效越好，但老年患者的效果相对较差。皮肤颜色较浅（III 型）且受累面积小于 10 cm² 的患者疗效更佳。合并黄褐斑的 ABNOM 患者疗效较差。受累区域的颜色或数量对疗效影响不大。约 10% 的患者在治疗后出现色素沉着。早期多次治疗可获得较好效果。皮肤颜色较深、斑块较深的老年患者更易在治疗后出现明显的色斑。对于同时患有 ABNOM 和黄褐斑的患者，建议使用较低能量的激光，以避免黄褐斑加重。
To evaluate the efficacy and safety of 1064-nm Q-switched Nd:YAG laser (QSNYL) therapy for ABNOM and to identify the factors influencing the outcome. A total of 110 patients with ABNOM were retrospectively evaluated and received two-to-nine treatment sessions. The curative effect was positively correlated with the treatment time and negatively correlated with the increasing age at first treatment (p < 0.05). The curative effect was better in patients with skin type III than those with type IV ( p < 0.05) and in patients with a lesion area of less than 10 cm2 than those with a larger affected area (p < 0.05). Additionally, the treatment effect was poorer in patients with concomitant melasma (p < 0.05). The treatment effect was not significantly correlated with the lesion color or number of affected sites (p > 0.05). Eleven patients (10%) developed postinflammatory hyperpigmentation (PIH). Early and repeated QSNYL therapy achieved satisfactory results for ABNOM. The risk of PIH after laser treatment is highest among patients with older age, darker lesion color, and darker skin color. For patients with ABNOM with concurrent melasma, low-energy laser therapy is recommended to reduce the risk of melasma aggravation.
To evaluate the efficacy and safety of 1064-nm Q-switched Nd:YAG laser (QSNYL) therapy for ABNOM and to identify the factors influencing the outcome. A total of 110 patients with ABNOM were retrospectively evaluated and received two-to-nine treatment sessions. The curative effect was positively correlated with the treatment time and negatively correlated with the increasing age at first treatment (p < 0.05). The curative effect was better in patients with skin type III than those with type IV ( p < 0.05) and in patients with a lesion area of less than 10 cm2 than those with a larger affected area (p < 0.05). Additionally, the treatment effect was poorer in patients with concomitant melasma (p < 0.05). The treatment effect was not significantly correlated with the lesion color or number of affected sites (p > 0.05). Eleven patients (10%) developed postinflammatory hyperpigmentation (PIH). Early and repeated QSNYL therapy achieved satisfactory results for ABNOM. The risk of PIH after laser treatment is highest among patients with older age, darker lesion color, and darker skin color. For patients with ABNOM with concurrent melasma, low-energy laser therapy is recommended to reduce the risk of melasma aggravation.
○ 治疗
美白剂的疗效有限。不同于黄褐斑，ABNOM可通过激光治疗显著改善，且去除后不易复发。通常需要进行10至20次激光疗程。
#QS1064 laser