Dermatofibroma - 皮肤纤维瘤
皮肤纤维瘤 (Dermatofibroma) 的典型病例 ― 肢体上出现硬结节。 皮肤纤维瘤 (Dermatofibroma)是一种比较常见的良性肿瘤。
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Dermatofibroma 是一种常见的皮肤病，主要出现在手臂或腿部。它表现为皮下坚硬的肿块，大小通常小于 1 厘米。虽然通常无痛，但可能与过去的轻伤有关，例如昆虫叮咬或刺刺。皮肤纤维瘤可能影响任何人，但在 20 至 40 岁的女性中更为常见。它们通常是良性的，但有时在切除后可能会复发。区分皮肤纤维瘤和更具侵袭性的皮肤肿瘤（称为 dermatofibrosarcoma protuberans ）很重要。
Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma. These mesenchymal cell lesions of the dermis clinically are firm subcutaneous nodules that occur on the extremities in the vast majority of cases and may or may not be associated with overlying skin changes. They are most commonly asymptomatic and usually relatively small, less than or equal to 1 centimeter in diameter. Often, patients who present with a dermatofibroma relate a history of possibly inciting local trauma at the site, such as from an insect bite or superficial puncture wound from thorns or wood splinters. Dermatofibromas occur in people of all ages, although more commonly during the ages of the 20s to 40s, and develop more frequently in females than males, with as high as a 2:1 female to male predominance according to some reports. They are a benign tumor, although there have been cases of local recurrence, and even more rarely, distant metastases have been reported. When considering the differential diagnosis of these lesions, it is vitally important to distinguish dermatofibromas from dermatofibrosarcoma protuberans, a similar-appearing but more aggressive cutaneous neoplasm.
Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma. These mesenchymal cell lesions of the dermis clinically are firm subcutaneous nodules that occur on the extremities in the vast majority of cases and may or may not be associated with overlying skin changes. They are most commonly asymptomatic and usually relatively small, less than or equal to 1 centimeter in diameter. Often, patients who present with a dermatofibroma relate a history of possibly inciting local trauma at the site, such as from an insect bite or superficial puncture wound from thorns or wood splinters. Dermatofibromas occur in people of all ages, although more commonly during the ages of the 20s to 40s, and develop more frequently in females than males, with as high as a 2:1 female to male predominance according to some reports. They are a benign tumor, although there have been cases of local recurrence, and even more rarely, distant metastases have been reported. When considering the differential diagnosis of these lesions, it is vitally important to distinguish dermatofibromas from dermatofibrosarcoma protuberans, a similar-appearing but more aggressive cutaneous neoplasm.
Lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, and epidermoid cysts 的首选治疗方法是手术切除。 Cherry angiomas and sebaceous hyperplasia 通常采用激光疗法或电干燥治疗。冷冻疗法和剃须切除是 acrochordons and seborrheic keratoses 的热门选择。如果家庭医生对诊断或治疗病变不确定，或者活检证实黑色素瘤，建议转诊给专科医生。
The preferred treatment for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, epidermoid cysts is surgical removal. Cherry angiomas, sebaceous hyperplasia are commonly treated with laser therapy or electrodesiccation. Cryotherapy and shave excision are popular choices for acrochordons, seborrheic keratoses. If a family physician feels uncertain about diagnosing or treating a lesion, or if a biopsy confirms melanoma, referral to a specialist is recommended.
The preferred treatment for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, epidermoid cysts is surgical removal. Cherry angiomas, sebaceous hyperplasia are commonly treated with laser therapy or electrodesiccation. Cryotherapy and shave excision are popular choices for acrochordons, seborrheic keratoses. If a family physician feels uncertain about diagnosing or treating a lesion, or if a biopsy confirms melanoma, referral to a specialist is recommended.
皮肤纤维瘤可能是对先前受伤（如昆虫叮咬或刺刺）的反应而形成的。皮肤纤维瘤被归类为良性皮肤病变，这意味着它们完全无害，尽管皮肤纤维瘤可能与各种皮下肿瘤混淆。即使在组织学上，深部穿透性皮肤纤维瘤也可能难以与罕见的恶性纤维组织细胞肿瘤（如“隆起性皮肤纤维肉瘤”）区分开来。
○ 诊断和治疗
大多数是良性的，但大病变（> 5毫米）可能需要活检。
#Dermoscopy
#Skin biopsy