Eczema herpeticum is a rare but severe disseminated infection that generally occurs at sites of skin damage produced by, for example, atopic dermatitis, burns, long term usage of topical steroids or eczema. It is also known as Kaposi varicelliform eruption, Pustulosis varioliformis acute and Kaposi-Juliusberg dermatitis.
Eczema herpeticum (EH) 是一种由单纯疱疹病毒在特应性皮炎患者中引起的广泛皮肤感染。它通常突然出现,在湿疹易发区域出现水疱样水疱和糜烂并结痂。症状可能包括发烧、淋巴结肿大或感觉不适。健康成人的 EH 可能是轻度和暂时性的,也可能是非常严重的,尤其是儿童、婴儿和免疫系统较弱的人。尽早开始抗病毒治疗有助于缩短轻症病例的时间并预防重症病例的并发症。 Eczema herpeticum (EH) is a disseminated cutaneous infection with herpes simplex virus that develops in a patient with atopic dermatitis. EH typically presents as a sudden onset eruption of monomorphic vesicles and punched-out erosions with hemorrhagic crusts over eczematous areas. Patients may have systemic symptoms, such as fever, lymphadenopathy, or malaise. Presentation ranges from mild and self-limiting in healthy adults to life-threatening in children, infants, and immunocompromised patients. Early treatment with antiviral therapy can shorten the duration of mild disease and prevent morbidity and mortality in severe cases.
一名患有特应性皮炎的 8 岁女孩来院时,身上出现大面积发痒、凸起的红色水泡,中间有一个小凹痕。测试显示她感染了1型单纯疱疹病毒。 An 8-year-old girl with atopic dermatitis came in with a widespread outbreak of itchy, raised, red blisters with a small indentation in the center. Tests showed she had herpes simplex virus type 1.
这种感染性疾病表现为特应性皮炎上叠加有大量水泡。它常伴有发烧和淋巴结肿大。疱疹性湿疹可能危及婴儿的生命。
这种情况最常见是由单纯疱疹病毒引起的。可以用全身抗病毒药物治疗,例如阿昔洛韦。
○ 诊断和治疗
误诊为湿疹皮损(特应性皮炎等)而应用类固醇软膏可能会加剧皮损。
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