Inflammatory Linear Verrucous Epidermal Nevus is a rare disease of the skin that presents as multiple, discrete, red papules that tend to coalesce into linear plaques that follow the Lines of Blaschko. The plaques can be slightly warty (psoriaform) or scaly (eczema-like). ILVEN is caused by somatic mutations that result in genetic mosaicism. There is no cure, but different medical treatments can alleviate the symptoms.
患者在5个月大时首次出现右前额头皮的黄色斑块。6个月后,头皮右后侧出现色素沉着过度的疣状丘疹。过去5年,这些斑点逐渐增大,但仅限于右侧面部、头皮和颈部。它们既不疼也不痒,患者生长发育正常。右脸颊和前额可见轻度凸起的黄色斑块,向头皮的正面和侧面延伸。与这些斑块相连的是色素沉着过度的疣状丘疹,形成从头皮后部至右侧颈部后部的线状分布。 The patient first showed up at five months old with yellow patches on the right front of the scalp. By six months, they had hyperpigmented verrucous papules on the back right side of the scalp. Over the past five years, these spots slowly grew bigger but stayed only on the right side of the face, scalp, and neck. They aren't painful or itchy, and the patient is growing normally. The right cheek and forehead have slightly raised, yellow patches that stretch onto the front and side of the scalp. Connected to these patches are hyperpigmented, verrucous papules, forming lines from the back of the scalp to the back of the neck on the right side.
○ 诊断和治疗
由于其外观与疣相似,需加以鉴别。表皮痣可通过激光消融予以去除。