Morphea, is a form of scleroderma that involves isolated patches of hardened skin on the face, hands, and feet, or anywhere else on the body, with no internal organ involvement.
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Scleroderma 是一种影响结缔组织的罕见疾病,表现为皮肤硬化,有时会波及身体其他部位。主要有两种类型:系统性硬化症(systemic sclerosis),涉及皮肤硬化和内脏器官;局灶性硬皮病(localized scleroderma),亦称硬斑病,通常仅限于皮肤及其下层组织,病程良性且自限。尽管局限性硬皮病并不常见,病因尚不明,但最新研究表明,它也可能累及内脏器官并引发多种健康问题。鉴于局灶性硬皮病的潜在严重性,早期治疗对预防并发症至关重要。 Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement, and localized scleroderma or morphea which classically presents benign and self-limited evolution and is confined to the skin and/or underlying tissues. Localized scleroderma is a rare disease of unknown etiology. Recent studies show that the localized form may affect internal organs and have variable morbidity. Treatment should be started very early, before complications occur due to the high morbidity of localized scleroderma.
Morphea,也称为局限性硬皮病,是一种影响结缔组织的罕见自身免疫性疾病。它可呈多种形式出现,且发病率不高,每10万人中约有0.4–2.7例。Morphea 常见于 2 至 14 岁的儿童,且女孩比男孩更易受影响。 Morphea (localized scleroderma) is a rare autoimmune connective tissue disease with variable clinical presentations, with an annual incidence of 0.4-2.7 cases per 100,000. Morphea occurs most frequently in children aged 2-14 years, and the disease exhibits a female predominance.
硬斑病是一种极为罕见的疾病。由于照片的构图,算法可能会误将其识别为硬斑病 (Morphea)。