Morphea - 硬斑病https://en.wikipedia.org/wiki/Morphea
硬斑病 (Morphea) 是硬皮病的一种,可使面部、手部、脚部或身体其他部位的皮肤变硬,但不累及内脏器官。硬斑病是由于胶原蛋白过度沉积而导致的皮肤和皮下组织增厚和硬化。硬斑病与“系统性硬化症”的区别在于不涉及内脏器官。

硬斑病是一种非常罕见的疾病。由于照片的构图,算法可能会将其误认为 硬斑病 (morphea) 。

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  • 硬斑病 (Morphea) 的病变通常表现为萎缩性色素斑块。
  • Frontal linear scleroderma
  • Frontal linear scleroderma
  • 变薄(或褪色)的黑白病变可疑硬斑病 (Morphea)。
References Localized scleroderma: clinical spectrum and therapeutic update 25672301 
NIH
Scleroderma 是一种影响结缔组织的罕见疾病,表现为皮肤硬化,有时会影响身体的其他部位。主要有两种类型: systemic sclerosis ,涉及皮肤硬化和内脏器官; localized scleroderma ,也称为硬斑病,通常仅限于皮肤及其下面的组织,具有良性和自限性病程。尽管局限性硬皮病并不常见,其病因尚不清楚,但最近的研究表明,它也会影响内脏器官并导致各种健康问题。鉴于 localized scleroderma 潜在的严重性,早期治疗对于预防并发症至关重要。
Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement, and localized scleroderma or morphea which classically presents benign and self-limited evolution and is confined to the skin and/or underlying tissues. Localized scleroderma is a rare disease of unknown etiology. Recent studies show that the localized form may affect internal organs and have variable morbidity. Treatment should be started very early, before complications occur due to the high morbidity of localized scleroderma.
 Upcoming treatments for morphea 34272836 
NIH
Morphea ,也称为局限性硬皮病,是一种影响结缔组织的罕见自身免疫性疾病。它可以以不同的方式出现,而且并不常见,每年每 10 万人中大约有 0. 4 - 2. 7 例。 Morphea 常见于 2 至 14 岁的儿童,并且女孩比男孩更容易受到影响。
Morphea (localized scleroderma) is a rare autoimmune connective tissue disease with variable clinical presentations, with an annual incidence of 0.4-2.7 cases per 100,000. Morphea occurs most frequently in children aged 2-14 years, and the disease exhibits a female predominance.