A neurofibroma is a benign nerve-sheath tumor in the peripheral nervous system. In 90% of cases, they are found as stand-alone tumors, while the remainder are found in persons with neurofibromatosis type I (NF1), an autosomal-dominant genetically inherited disease. They can result in a range of symptoms from physical disfiguration and pain to cognitive disability.
Neurofibromas 是周围神经中常见的良性肿瘤,通常表现为皮肤表面的软性肿块或皮肤下的细小结节。它们起源于神经内膜及周围神经鞘周围的结缔组织。 Neurofibromas are the most prevalent benign peripheral nerve sheath tumor. Often appearing as a soft, skin-colored papule or small subcutaneous nodule, they arise from endoneurium and the connective tissues of peripheral nerve sheaths.
神经纤维瘤 (neurofibroma) 的直径通常为 2 至 20 毫米,质地柔软、松弛,呈粉白色。活检可用于组织病理学诊断。
神经纤维瘤 (neurofibroma) 多在青少年期出现,常在青春期后被发现。患有 I 型神经纤维瘤病的人群中,肿瘤的数量和大小往往在成年期持续增长。