A neurofibroma is a benign nerve-sheath tumor in the peripheral nervous system. In 90% of cases, they are found as stand-alone tumors, while the remainder are found in persons with neurofibromatosis type I (NF1), an autosomal-dominant genetically inherited disease. They can result in a range of symptoms from physical disfiguration and pain to cognitive disability.
Neurofibromas 是周围神经中常见的良性肿瘤。它们通常看起来像皮肤上的软肿块或皮肤下面的小肿块。它们由神经内膜和周围神经鞘周围的结缔组织发育而来。 Neurofibromas are the most prevalent benign peripheral nerve sheath tumor. Often appearing as a soft, skin-colored papule or small subcutaneous nodule, they arise from endoneurium and the connective tissues of peripheral nerve sheaths.
神经纤维瘤 (neurofibroma) 直径可能为 2 至 20 毫米,柔软、松弛、粉白色。活检可用于组织病理学诊断。
神经纤维瘤 (neurofibroma) 通常出现在青少年时期,并且通常发生在青春期之后。在患有 I 型神经纤维瘤病的人中,它们的数量和大小往往会在整个成年期持续增加。